113 - Syncope Flashcards

1
Q

What is syncope?

A

A transient loss of consciousness (TLoC)

due to: transient global cerebral hypoperfusion

Characterised by: rapid onset, short duration, spontaneous complete recovery

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2
Q

What is pre-syncope?

A

Nearly syncope

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3
Q

What differentials are there for syncope?

A

Epilepsy, Metabolic disorders, hypoxia, hypoglycaemia, vertebro-basilar TIA, psychogenic?

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4
Q

What other names are there for vasovagal syncope?

A

Reflex syncope

Neuronaly mediated syncope

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5
Q

What is vasovagal syncope?

A

History of syncopy with an absence of cardiac disease

Occurs after standing, noxious stimulus, nausea and vomitting, after exertion, after heat.

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6
Q

What is cardiac syncope?

A

Known history of cardiac disease.
Evidence of structural abnormalities
Chest pain, palpitations
During exercise

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7
Q

What investigations could you do in syncope?

A
History
ECG
Echocardiogram
Tilt test
CXR
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8
Q

What is an ECG

A

Records electrical activity of the heart

Looks at sum total of electrical signals at a moment in time - coming towards the electrode

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9
Q

What leads does a 12 lead ECG have?

A

3 Bipolar limb leads (I, II, III)
3 unipolar augmented lumb leads (aVr, aVl, aVf)
Chest leads (V1-6)

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10
Q

Which leads do you get a horizontal view of the heart?

A

Chest leads V1-6

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11
Q

Which leads are prominent if the heart is orientated correctly?

A

If lead I and II are prominently positive in QRS - probably normal

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12
Q

What is occuring at each stage of the ECG wave?

A
p = atrium depolarising
PR = gap while signal delayed in AV node
QRS = ventricles depolarising
t = ventricles repolarising
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13
Q

What is the cardiovascular system?

A

A convective transport system - driven by pressure difference in systemic system
In cells/microvessels = diffusion transport system

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14
Q

How do you measure blood presure?

A

sphygmomanometry

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15
Q

What does the systolic pressure represent?

A

Ventricles contracting, mitral + tricuspid contract

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16
Q

What does diastolic pressure represent?

A

Atrium contracting, aortic and pulmonary valves shut, aorta relaxes

17
Q

What is the pulse pressure?

A

The difference between systolic and diastolic pressure

18
Q

How do you calculate mean arterial pressure?

A

Diastolic + 1/3 pulse pressure

or

Pa = CO x total peripheral resistance

19
Q

What is central venous pressure?

A

LOW - around 2 mmHg

20
Q

What is darcy’s law?

A

Flow = pressure change / resistance

21
Q

What is compliance?

A

Measure of expandability - veins -> high->flexible

Arteries -> low -> stiff

22
Q

Which arteries are elastic? What effect does this have?

A

Aorta/Large arteries

Windkessel effect - smooths out wave, by storing elastic energy, increasing efficiency

23
Q

Which arteries are conduit arteries? What are their characteristics?

A

large/medium arteries

Muscle prevents collapse
Less elastin
Smaller tunica media

24
Q

Which vessels are resistance vessels?

A

Small arteries and arterioles
Muscle tone regulates blood flow
Thick walls compared to lumen

25
Which vessels are exchange vessels?
Capilleries
26
Which vessels are capitance vessels?
Veins Provide a resevoir of blood can collapse 60-70% of blood stored in them
27
What are the 3 blood pumps of the body?
Heart Skeletal muscle pump Respiratory pump
28
How is blood flow distributed through organs?
By resistance
29
How are the pulmonary and systemic systems arranged?
In series
30
How are organs in the systemic system arranged?
In parallel
31
How is blood pressure regulated in the short term? Where are receptors located?
Baroreceptor reflex: Baroreceptor -> medulla -> ANS -> SA node - Atrial stretch receptors - L ventrical/coronary artery stretch receptor - Aortic arch baroreceptors - Carotid sinuses
32
Which nerves nerves take the impusles from the baroreceptors to the ANS?
Vagus nerve | Glossopharangeal nerve
33
What happens when arterial pressure increases in the baroreceptor reflex?
Increase impulses, Increase stimulation, Increase PARASYMPATHETIC NS -> decrease HR at SA node and vasodilate
34
What happens when arterial pressure decreases in the baroreceptor reflex?
Reduce impulses, reduce stimulation, increase SYMPATHETIC, increase HR, contractibility + vasoconstriction
35
What are the long term ways BP is regulated?
Osmoregulation Pressure Natriuresis Renin-Angiotensin-Aldesterone