renal cell carcinoma Flashcards
1
Q
what is a renal cell carcinoma?
A
- adenocarcinoma of the renal cortex
- most common type of kidney tumour
2
Q
RCC risk factors
A
- smoking
- renal failure and dialysis
- obesity
- hypertension
- low socio economic status
- asbestos, cadmium exposure, phenacetin
- genetic (VHL accounts for most sporadic renal cancers and 50% of VHL syndrome will develop RCC)
3
Q
where do RCC arise from
A
proximal convoluted tubule
4
Q
True/False
Some RCCs contain cysts
A
True
10-25% contain cysts or are predominantly cystic
5
Q
how is the difference between cystic kidney disease and cancer predicted?
A
using the Bosniak score
6
Q
types of RCC?
A
- Conventional clear cell carcinoma (80%)
- Papillary (10-15%)
- Chromophone (5%)
- Collecting duct
- Medullary cell
