5

Question 1

What is the locally malignant tumer ?

Answer 1

Giant cell tumor

Question 2

Carcinoma of Prostate, Breast, Lung, Thyroid, Kidney is ?

Answer 2

Secondary Bone Tumors (Metastases)

Question 3

What is the stain of Ewing’s Sarcoma ?

Answer 3

Periodic acid–Schiff (PAS) stain is positive due to presence of glycogen in cells

Question 4

What is the Origin and Sites and Age of Ewing’s Sarcoma ?

Answer 4

origin is unsettled; recently believed to be of neural origin , arises in medullary cavity in the diaphysis of long bone
Age : 5-20 years

Question 5

Osteolytic bone lesion with onionskin-like appearance is in ?

Answer 5

Ewing’s Sarcoma

Question 6

What is the Radiological Features of Giant Cell Tumor (Osteoclastoma) ?

Answer 6

large Osteolytic lesion with soap-bubble appearance

Question 7

Benign tumor composed of hyaline cartilage ?

Answer 7

Chondroma (Enchondroma)

Question 8

Benign bony outgrowth (exostosis) capped with cartilage ?

Answer 8

Osteochondroma (Exostosis)

Question 9

What is the site of Osteoid Osteoma ?

Answer 9

cortex of proximal femur and tibia

Question 10

What is the site of Osteoid Osteoblastoma ?

Answer 10

arise most often in the Vertebra

Question 11

multiple Osteoma is ?

Answer 11

Gardner syndrome

Question 12

Example of Multiple enchondromas ?

Answer 12

Ollier disease

Question 13

What is the gross of Chondroma (Enchondroma) ?

Answer 13

capsulated, rounded or lobulated mass the cut surface is bluish grey, translucent

Question 14

What is the Radiological Features of Ewing’s Sarcoma ?

Answer 14

Osteolytic bone lesion with onionskin-like appearance around bone.

Question 15

What is the Radiological Features of OSTEOSARCOMA (Osteogenic Sarcoma) ?

Answer 15

1- Sun ray appearance

2- Codman’s triangle

Question 16

What is the site of OSTEOSARCOMA (Osteogenic Sarcoma) ?

Answer 16

distal end of femur & proximal end of tibia (around knee; 60% )

Question 17

What is the age of primary OSTEOSARCOMA ?

Answer 17

10 - 20 years

Question 18

What is the Radiological Features of CHONDROSARCOMA ?

Answer 18

Radiolucent mass with scattered dense foci (due to spotty calcifications)

Question 19

What is the age of CHONDROSARCOMA ?

Answer 19

40-60 years

Question 20

What is the origin of Multiple Myeloma ?

Answer 20

Malignant plasma cell tumor occurring in bone marrow →→

→ secrete kappa (κ) or lambda (λ) light chains (Bence-Jones proteins)

Question 21

What is the Microscopy of Multiple Myeloma ?

Answer 21

Malignant plasma cells; at different stages of maturation.

Question 22

What is the Radiology of Multiple Myeloma ?

Answer 22

Multiple Osteolytic bone lesions.

Question 23

Bone and bone marrow destruction due to multiple myeloma leading to:

Answer 23

1- Bone pain , may be Pathological fractures.
2- Pancytopenia
3- Hypercalcaemia

Question 24

Production of abnormal immunoglobulins (Bence-Jones proteins) due to multiple myeloma is ?

Answer 24

1- Bence-Jones proteinuria
2- low immunity
3- Primary Amyloidosis ( AL (Amyloid light chain) protein )