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Question 1

In MUSCULAR DYSTROPHY the advanced cases muscle fibers are replaced by ?

Answer 1

fibro-fatty tissue

Question 2

What is the Two most common forms of muscular dystrophy are X-linked ?

Answer 2

1- Duchenne muscular dystrophy (DMD):
- the most severe & the most common

2- Becker muscular dystrophy (BMD):
- less common and much less severe.

Question 3

What is the Microscopic of Duchenne muscular dystrophy (DMD) ?

Answer 3

1- marked variation in muscle fiber size
2- Many muscle fibers show → degenerative changes and necrosis
3- ↑ interstitial fibrosis & fatty tissue infiltration in most muscles
→ Produces pseudohypertrophy of calf muscles