Lecture 2 - Glomerular Filtration Flashcards
What is the glomerulus ?
Blood vessels/ capillaries
What’s the function of the collecting tubule?
Collects the waste and send thru the ureters to the bladder
Why is ammonia/NH3+ converted to urea and Uric acid?
As more urea can be stored than nh3+
Nh3+ can cause pH changes in the blood
What’s known as urine waste?
Toxins
Urea
Nitrogenous waste
What does not get filtered in the plasma? And why?
Proteins and RBC’s bc they are so big
What’s the function of the glomerulus?
Provides the blood that gets filtered
What is the visceral layer?
Inner wall of the bowman’s capsule, lines the glomerular capsule
Whats the parietal layer?
Outer wall of the bowman’s capsule
Whats the two layers of the bowman’s capsule?
Visceral and parietal
What are podocytes and where are they found?
Specialised cells that have large splits that aid filtering
In the Bowman’s capsule that touch the capillaries
What are the three layers of filtration barriers?
Endothelium
Basement membrane
Podocytes
How does filtration occur in the endothelium
High hydrostatic pressure pushing filtrates thru the pores
What part of the filtration barrier stops proteins from escaping the capillaries? And why?
Basement membrane
Due to the negatively charged proteoglycans
What arteriolar is wider and narrower?
Wider - afferent
Narrower - efferent
Why is efferent arteriol narrower? And why?
To create higher hydrostatic pressure
So fluids enter the bowman’s capsule
