Malignant Non Od. Ct

Question 1

Kaposi sarcoma ttt?

Answer 1

Radio+chemo

Question 2

Histology of patch kaposi?

Answer 2

Mass of irregular capillaries with perivascular cuffing by plasma cells & lymphocytes. Proliferation of fine vessels surrounding pre-existing vessel.

Can’t be differentiated from pyogenic granuloma.

Question 3

Histology of nodular and plaque kaposi sarcoma?

Answer 3

2. Plaque stage →> proliferation of spindle cells (endothelial cells).
3. Nodular stage:

↑proliferation of spindle cells.

↑extravasated RBCs around slit like vascular spaces.

↑signs of malignancy (mitosis).

Question 4

Features of Hodgkin lymphoma

Answer 4

1- night sweating
2-weight loss
3- happens  only in cervical lymph nodes and really in the  cavity
4- low grade fever
5-adults

Question 5

Characteristic features of burkitt’s lymphoma

Answer 5

• centrally in max >mand
• cause facial swelling
• proptosis
• mild pain and parathesia
• mobility and resorption of roots

Question 6

Characteristic features of non Hodgkin lymphoma

Answer 6

• oral and extraoral
• cervical axillary and abdominal Ln
• orally in post 1/3of tongue and soft palate
• also centrally in the jaw
• only ulcerated by trauma
• slow and painless

Question 7

Marker for kaposi

Answer 7

Factor 8

Question 8

Non h lymphoma marker

Answer 8

Leukocyte common antigen LCA

Question 9

Histology of malignant fibrous histiocytoma?

Answer 9

Formed of 2 types of cells (fibroblasts & histiocytes).

Thin Bundle

4 Types:

1. Storiform pleomorphic (most common) → short fascicles of spindle shape fibroblasts in storiform pattern admixed with histiocytes both showing signs of malignancy.
2. Giant cell type →→ contain giant cells.
3. Myxoid type → contain myxoid tissue.
4. Angiomatoid type → contain blood vessels.

Question 10

Liposarcoma subtypes?

Answer 10

H/P:

Ⓒ Presence of lipoblasts (lipid forming cell) showing signs of

malignancy.

Dissolution of fat content of the cell around darkly stained

nucleus → signet ring appearance.

O Types:

1. Well differentiated type.

o As lipoma formed of scattered lipoblasts showing signs of malignancy (hyperchromatic neoclei).

2. Dedifferentiated type:

Tumor with parts well differentiated & other parts poorly

differentiated.

3. Myxoid type:

Most common type intraorally.

o Contain proliferating lipoblasts within myxold stroma that contain

rich capillary network giving Chicken footprint appearance.

4. Round cell type:

Ⓒ Most aggressive form. Round shape cell (poorly

differentiated) & increase signs of malignancy.
5. Pleomorphic type:

O Increase in cellular pleomorphism & bizarre giant cells.