Benign Epi. Non Odontogenic Neoplasm

Question 1

Clinical picture of sq. Cell papilloma

Answer 1

1- Age- anyage mostly 4t-5” decades.

2- Sex- males - females. 3- Site buccal mucosa, gingiva, palate, lips and

tongue.

4- Size small (few millimeters to 3 cm). 5- Exophytic papilliferous growth made of

finger like projections givine (cauliflower

like or wart appearance).

6-Mainly solitary but may be multiple

in

immunosuppressed patients. 7- Mainly pedunculated or may be sessile.

8- Painless, non-contagious 9- Color reddish or whitish or same color as

oral mucosa.

Question 2

Etiology of sq.c . Papilloma

Answer 2

Human papilloma virus (HPV-6 & HPV-11) in (50% of cases. Origin Is surface squamous epithelium.

Epidemiology → 3% of oral lesions.

Question 3

Could sq.c.papilloma reoccur?

Answer 3

Good prognosis (rare recurrence) except in laryngeal cases.

Question 4

Is keratoacanthoma benign or malignant?

Answer 4

> Some consider it as a benigni lesion resembling squamous cell carcinoma clinically and histologically, while others consider it a variant of sq.c.c
That can be self limiting

Question 5

Causes of keratoacanthoma?

Answer 5

• hpv 9.11.13
• sun damage
• immuno suppression
• trauma
• genetic factors
• chemicals

Question 6

Keratoacanthoma clinically is distinguished by?

Answer 6

-exophytic
-creater like
-sessile firm nodule with depression that contain black to brown plug
-not tinder but painful with lymphadenopathy
-in pielosebaceous glands in vermilion border and skin of H and N
-males to female 2 to 1
-age 50 to 70
-stages of growth:
1- growth stage– 4 to 6 w
2- stationary —stable for 6w
3-in volition phase – spontaneous regression in 6 to 12 m
Leaving a depressed scar after keratin plug expulsion

Question 7

Treatment of keratoacanthoma

Answer 7

O

Differential diagnosis:

KERAT

Squamous cell carcinoma.

Verrucous carcinoma.

O Only large lesionsurgical excision to avoid scar formation. o Recurrence may occur with rare malignant transformation.

Question 8

Focal epithelial hyperplasia vs errucous vulgaris in cause

Answer 8

• –Heck–
• hpv 13 and 32
• genetic background
• mal nutrition
• poor hygiene
• low socioeconomics
• –Verrucous vulgaris —
• hpv 40 and 4
• homeless
• poor hygiene

Question 9

Focal epithelial hyperplasia vs errucous vulgaris site ?

Answer 9

H–
-LOWER LIP

VV—

• all skin specially hand and feet
• oral cavity by auto inucleation

Question 10

Focal epithelial hyperplasia vs errucous vulgaris in histopathology

Answer 10

H–
-same as common warts but with no hyper keratosis

Vv—
-same as sq.c.papilloma

Question 11

Focal epithelial hyperplasia vs errucous vulgaris in contagion and age

Answer 11

Same age both children

H—-
- non contagious

Vv—
Contagious

Question 12

Focal epithelial hyperplasia vs errucous vulgaris shape

Answer 12

H–
Multiple pale and rough or smooth

Vv- solitary or multiple sessile