Vitamin B5 - Pantothenic Acid Flashcards
Vitamin B5 - Pantothenic Acid
• Vitamin B5 (pantothenic acid) is required to make coenzyme A (CoA) the same CoA that forms acetyl CoA (needed for ATP production). In this active form it is involved in hundreds of different reactions.
Vitamin B5- Food Sources
- Richest food sources include shiitake mushrooms, avocados, nuts, seeds, fish and meat. However, it is found widely distributed in almost all foods hence the name.
- Synthesised by intestinal bacteria, but to as yet unknown level of absorption. Theoretically, antibiotics may reduce synthesis
Vitamin B5 - Food prep
• Sensitive to processing, cooking and freezing with up to 80% loss.
Vitamin B5 - Roles
ATP Production
Fat Metabolism
Stress hormones
Anti-histamine
Vitamin B5: ATP Production - Functions
- Metabolism of carbohydrates and proteins.
* Required for Acetyl CoA formation
Vitamin B5: ATP Production: Therapeutic Uses
Fatigue
Supporting energy production in increased need
Vitamin B5: Fat Metabolism - Functions
The synthesis and degradation of fatty acids.
Vitamin B5: Fat Metabolism - Therapeutic Uses
Acne Vulgaris
Vitamin B5: Stress Hormones - Functions
- Acetyl CoA -> neurotransmitters (i.e. increased GABA)
* A cofactor for stress hormones (used up quickly when stressed)
Vitamin B5: Stress Hormones - Therapeutic Uses
Adrenal Fatigue
Vitamin B5: Anti-histamine - Functions
Antihistamine properties
Vitamin B5: Antihistamine - Therapeutic Uses
Allergies
Hay Fever
Vitamin B5 Deficiency
- Deficiency is rare. However, depletion may occur with high alcohol use, prolonged stress and recent surgery.
- Deficiency Symptoms: burning sensation in feet and tender heels, fatigue and abdominal distress.
Vitamin B5 - Toxicity
No known toxicity
