Ondansetron Flashcards
1
Q
ONDANSETRON
Pharmacology & Actions
A
- Selectively blocks serotonin 5-HT3 receptors in the brain
- Primary effect is in the GI tract
- No effect on dopamine receptors and therefore does not cause extrapyramidal symptoms
2
Q
ONDANSETRON
Indications
A
- Nausea or vomiting
3
Q
ONDANSETRON
Absolute Contraindications
A
- Patients with prolonged QT
- Patients < 1 month old
- Ondansetron allergy
4
Q
ONDANSETRON
Precautions & Side Effects
A
- May cause QT prolongation, avoid use in patients with prolonged QT syndrome
5
Q
ONDANSETRON
Administration
A
- IV/PO/SL
- Onset: 10-30 min
- Peak Effect: 1.5 hrs
- Duration: 8 hrs
