Nitrates Flashcards
1
Q
Interactions of nitrates • Methotrexate • Warfarin • Phosphodiesterase inhibitor • Prednisolone • Antihypertensives
A
- Phosphodiesterase inhibitor
* Antihypertensives
2
Q
Short acting nitrates name • GTN • ISMN • ISDN • All of the above
A
• GTN
3
Q
Warnings with nitrates • SAS • Hypertension • Haemodynamic instability • Hypotension
A
- SAS
- Haemodynamic instability
- Hypotension
4
Q
MOA of nitrates
• Relaxation and vasodilation in arterial smooth muscle
• Relaxation of the venous capacitance vessels
• Increase cardiac preload and left ventricular filling
• Reduce cardiac preload and left ventricular filling
• Dilation of capacitance veins
• Reduce cardiac work and myocardial oxygen demand
A
- Relaxation of the venous capacitance vessels
- Reduce cardiac preload and left ventricular filling
- Reduce cardiac work and myocardial oxygen demand
5
Q
SE of nitrates • Tolerance • Bradycardia • Light-headness • Flushing • Palpitations • Hypotension
A
- Tolerance
- Light-headness
- Flushing
- Hypotension
6
Q
Long acting nitrates • ISMN • GTN • ISDN • All of the above
A
• ISMN
7
Q
Uses of GTN • Acute angina • Prophylaxis of angina • ACS • Pulmonary oedema • All of the above
A
- Acute angina
* ACS
8
Q
Uses of ISMN • Acute angina • Prophylaxis of angina • ACS • Pulmonary oedema • All of the above
A
• Prophylaxis of angina
9
Q
IV nitrates are used for . Acute angina • Prophylaxis of angina • ACS • Pulmonary oedema • All of the above
A
• Pulmonary oedema
10
Q
Administration of IV nitrates require monitoring of what • U&E’s • Renal function • eGFR • blood test • Blood pressure
A
• Blood pressure <90
