thiazide diuretics Flashcards
1
Q
Name the thiazide diuretics • Indapamide • Co-amilozide • Chlortalidone • Co-amiloride • Bendroflumethiazide • A,b,c
A
- Indapamide
- Chlortalidone
- Bendroflumethiazide
2
Q
Uses of thiazide diuretics • Oedema • Hypokalaemia • Hypertension • Hypotension
A
• Hypertension
3
Q
MOA of diuretics • Inhibit Na, Cl co-transporter in distal convoluted tub • Counteract potassium loss • Act on convoluted tubules in kidney • Prevents reabsorption of sodium • Sodium and water excretion • Fall in extracellular fluid volume • Potassium retention • Vasodilation
A
- Inhibit Na, Cl co-transporter in distal convoluted tubules
- Prevents reabsorption of sodium
- Fall in extracellular fluid volume
- Vasodilation
4
Q
SE • Gout • Cardiac arrhythmias • Hypovolaemia • Hyponatraemia • Electrolyte disturbance • Hypokalaemia • Impotence
A
- Cardiac arrhythmias
- Hyponatraemia
- Hypokalaemia
- Impotence
5
Q
WARNINGS • Severe renal impairment • Hyponatraemia • Hypokalaemia • Hyperkalaemia • Gout
A
- Hyponatraemia
- Hypokalaemia
- Gout
6
Q
Interactions • NSAIDs • Potassium elevating drugs • Aldosterone antagonist • Loop diuretics • lithium
A
- NSAIDs
* Loop diuretics
