Lung Surfactant Flashcards
1
Q
Cells that produces surfactant
A
Type 2 Pneumocytes
2
Q
MAIN component of surfactant
A
WATER
3
Q
ACTIVE component of surfactant
A
DIPALMITOYL-PHOSPHATIDYLCHOLINE (DPPC)
4
Q
Mechanism for DPPC reducing surface tension
A
Amphipathic nature (HYDROPHOBIC and HYDROPHILIC)
5
Q
Effect of surfactant on Lung Compliance
A
INCREASE compliance
6
Q
START of surfactant production
A
24TH WEEK AOG
7
Q
MATURATION of surfactant
A
35TH WEEK AOG
8
Q
DEFICIENCY in surfactant causes
A
NEONATAL RESPIRATORY DISTRESS SYNDROME (RDS)
9
Q
Test for surfactant
A
Amniotic Lecithin:Sphingomyelin Ratio (Ratio of 2:1 or GREATER = MATURE fetal lungs)
10
Q
Treatment for newborn RDS
A
STEROIDS
SURFACTANT
