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MNI pharm > Antibacterial Regimens > Flashcards

Antibacterial Regimens Flashcards

1
Q

Bacterial endocarditis empiric therapy

A

Vancomycin and gentamicin

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2
Q

endocarditis in the presence of a prosthetic heart valve

A

Add Rifampin to gentamicin/vancomycin regimen

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3
Q

Endocarditis treatment for patients with
intolerance to vancomycin

A

Linezolid or daptomycin

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4
Q

What is the antibacterial treatment for infective
endocarditis caused by a-hemolytic streptococci?

A

Penicillins (penicillin G and ampicillin) often in
combination with gentamicin.

Or

IV gentamicin

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5
Q

antibacterial treatment for infective
endocarditis caused by Staphylococcus aureus?
Oxacillin-Susceptible Strains

A

Nafcillin or oxacillin

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6
Q

antibacterial treatment for infective
endocarditis caused by Staphylococcus aureus for Penicillin-allergic (nonanaphylactoid) patients

A

Cefazolin

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7
Q

antibacterial treatment for infective
endocarditis caused by Staphylococcus aureus for Oxacillin-Resistant Strains

A

Vancomycin

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8
Q

When is bacterial endocarditis prophylaxis needed ?

A

oral-dental procedures in patients with
- Prosthetic cardiac valves
- Previous infective endocarditis
- Congenital heart disease (CHD)
- Cardiac transplant recipients with valvulopathy

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9
Q

Recommended Endocarditis Prophylaxis During Oral-Dental or Respiratory Tract Procedures

A

Amoxicillin

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10
Q

Recommended Endocarditis Prophylaxis During Oral-Dental or Respiratory Tract Procedures. With penicillin allergy

A

Clindamycin or Cephalexin or Azithromycin or Clarithromycin

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11
Q

Bacterial pharyngitis

A

Penicillin V and Amoxicillin
Alternatives

  • Macrolide (penicillin-allergic patients)
  • Clindamycin
  • First or second generation cephalosporin
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12
Q

Bacterial Sinusitis

A

Amoxicillin
Alternative agents include:
- Amoxicillin-clavulanic acid
- Macrolide (penicillin-allergic patients)
- Co-trimoxazole
- Second or third generation cephalosporin

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13
Q

Acute otitis media therapy

A

Amoxicillin
Alternative agents include:
- Amoxicillin-clavulanic acid
- Macrolide (penicillin-allergic patients)
- Clindamycin
- Second or third generation cephalosporin

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14
Q

Community acquired pneumonia in previously healthy person

A

Macrolide or doxycycline

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15
Q

Community acquired pneumonia in immunosuppressed

A

Respiratory fluoroquinolone
or
b-lactam plus a macrolide

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16
Q

Community acquired pneumonia in non icu

A

Respiratory fluoroquinolone
or
b-lactam plus a macrolide

17
Q

Community acquired pneumonia in an icu

A

• b-lactam plus either azithromycin
or a respiratory fluoroquinolone
• For penicillin-allergic patients, a
respiratory fluoroquinolone plus
aztreonam

18
Q

Aspiration pneumonia

A

Clindamycin or metronidazole

19
Q

Bordetella pertussis

A

Macrolide or co-trimoxazole

20
Q

Chlamydia pneumoniae

A

Macrolide
Doxycycline
3rd or 4th generation fluoroquinolone

21
Q

Haemophilus influenzae (otitis media, sinusitis)
Non beta lactamase producing

A

Amoxicillin

22
Q

Haemophilus influenzae (otitis media, sinusitis)
beta lactamase producing

A

2nd or 3rd generation
cephalosporin, amoxicillin clavulanic acid

23
Q

Klebsiella pneumoniae

A
24
Q

Legionella sp

A
25
Q

Mycoplasma pneumoniae

A

Macrolide or doxycycline

26
Q

Pseudomonas aeruginosa

A

Antipseudomonal penicillin, ciprofloxacin

27
Q

Staph aureus

A

Methicillin susceptible
penicillin or 2nd or 3rd generations cephalosporin, clindamycin, fluoroquinolone, imipenem

Methicillin resistant
Vancomycin, linezolid or Ceftaroline

28
Q

Streptococcus pneumonia

A

Penicillin G, amoxicillin or
cephalosporins, Clindamycin,fluoroquinolone, macrolide, Cotrimoxazole

If penicillin resistant
Cephalosporins and Fluoroquinolones
Or vancomycin, linezolid

29
Q

Tularemia

A

Streptomycin

30
Q

Treatment of C.difficile

A

Vancomycin and Fidaxomicin

*Caused by clindamycin

31
Q

What is the drug of choice for traveler’s diarrhea?

A

Ciprofloxacin in non children

Alternative agents include:
- Amoxicillin
- Azithromycin
- Doxycycline

32
Q

Bacteroides

A
  • Metronidazole
  • Carbapenems
  • Clindamycin
  • Beta-lactam plus beta-lactamase inhibitor
33
Q

Giardia

A

Metronidazole

34
Q

Campylobacter

A

Azithromycin

35
Q

C.perfringens

A

Penicillin, clindamycin

MNI pharm (7 decks)

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