Cell structure and function

Question 1

Examples of Peripheral Proteins

Answer 1

1) Cytochrome C (electron carrier)
2) Annexins (Ca2+ lipid binding protein)
3) Synapsin 1 (binds vesicles to cytoskeleton)
4) Spectrin (stabilizes membrane of erythrocytes)

Question 2

Actin, Actinin, Vinculin, Talin

Answer 2

1) Non erythroid spectrin
2) Cross-links actin
3) Binds alpha-actinin to talin
4) Attaches integrin to p.m.

Question 3

Glycocalyx

Answer 3

Functions in preventing injury and antigen binding (T cells)

Question 4

In Desmosomes, we have proteins called dense plaques that…?

Answer 4

Anchor cadherins

Question 5

1) Outer nuclear envelope surrounded by IF’s?
2) Inner nuclear envelope has IF’s?
3) Separated by?

Answer 5

1) Vimentin
2) Nuclear Lamina
3) Perinuclear cisterna

Question 6

Site of ribosome biogenesis? (Hint: nucleus)

Answer 6

Nucleolus

Question 7

3 components of nucleolus

Answer 7

1) Fibrillar: early rRNA formation
2) Granular: late rRNA formation
3) Nuclear-associated chromatin: DNA

Question 8

Outer membrane of mitochondria contains proteins called?

Answer 8

Porin (cytosol > inter-membrane space)

Question 9

Ribosomes bind to RER via

Answer 9

Ribophorins

Question 10

1) Primary lysosome
2) Secondary lysosome
- Heterophagic vacuole
- Autophagic vacuole
- Multivesicular body

Answer 10

1) New unengaged vesicles
2) Digestive activity
- Outside material engulfed, fuse with 1 lysosome
- Organelles engulfed, fuse with 1 lysosome
- Fluid enveloped, fuse with 1 lysosome

Question 11

Hydrogen peroxide breakdown via?

Answer 11

Catalase

Question 12

Inclusions are…

Answer 12

Materials in cytoplasm that may/not be surrounded by membranes
(glycogen, lipid droplets)