NMS vs. Serotonin Syndrome

Question 1

NMS is more likely to happen with what agents?

Answer 1

Dopamine antagonists (APS!), more likely in high potency drugs like fluphenazine and haloperidol in FGAs

Question 2

Time of onset of NMS

Answer 2

~1-3 days

Question 3

Does NMS have hypo or hyperreflexia?

Answer 3

HYPOreflexia

Question 4

Does NMS have normal or dilated pupils?

Answer 4

Normal (N in NMS, N in normal!)

Question 5

Does NMS have normal/decreased bowel sounds or hyperactive bowel sounds?

Answer 5

Normal/decreased (N in NMS for normal!)

Question 6

NMS mental status

Answer 6

Variable ranging from alert to stupor or coma

Question 7

Other NMS symptoms

Answer 7

lead pipe rigidity, pallor

Question 8

Serotonin syndrome is more likely to happen with what agents?

Answer 8

Serotonin agents

Question 9

Time of onset for serotonin syndrome

Answer 9

<12 hours

Question 10

Does SS have hypo or hyperreflexia?

Answer 10

HYPERreflexia and clonus (2 Ss, 2 Rs)

Question 11

Does SS have normal or dilated pupils?

Answer 11

Dilated

Question 12

Does SS have normal/decreased bowel sounds or increased bowel sounds?

Answer 12

Increased/hyperactive

Question 13

SS mental status

Answer 13

Variable ranging from agitation to coma

Question 14

Other SS symptoms

Answer 14

Increased tone in lower extremities

Question 15

What do NMS and SS have in common?

Answer 15

HTN, increased HR, hyperthermia, hypersalivation, diaphoresis