Anticoagulants Flashcards
0
Q
thrombosis
A
the presence of a thrombus
1
Q
anticoagulants (6)
A
-ind. for thrombosis Coumadin Pradaxa Xarelto Lovenox Eliquis Arixtra
2
Q
thrombus
A
blood clot
3
Q
Do anticoagulants dissolve thrombi?
A
no, they only keep them from getting bigger
4
Q
Coumadin
A
warfarin
- Vitamin K antagonist
- qday
- inhibits the synthesis of the Vit. K-dependent clotting factors (II, VII, IX, and X)
- pt. counseling: do NOT change diet while on Coumadin
- -increasing Vit. K intake could decrease Coumadin effectiveness
- -check multivitamins to be sure they do not include Vit. K
5
Q
Mephyton
A
phytonadione
- Vit. K in tablet form
- reverses effects of Coumadin in OD
6
Q
MOA of Vitamin K antagonists
A
decrease clotting factors which decreases clot formation
7
Q
Pradaxa
A
dabigatran
- thrombin inhibitor
- BID
- 75mg, 150mg cap
- dispense in original container* once exposed to atmospheric moisture it is only good for four months
8
Q
thrombin inhibitor MOA
A
inhibits thrombin which is an enzyme necessary for fibrin formation
9
Q
fibrin
A
necessary for clot formation
10
Q
Xarelto
A
rivaroxaban
- factor Xa inhibitor
- 10mg tab qday
11
Q
factor Xa inhibitor MOA
A
inhibiting clotting factor Xa will inhibit clot formation
12
Q
Eliquis
A
apixaban
- factor Xa inhibitor
- 2.5mg, 5mg tab BID
13
Q
Arixtra
A
fondaparinux
-parenteral factor Xa inhibitor
