Mapping Flashcards

1
Q

Genetic and physical maps differ in that _____.

A. the order of the genes are reversed

B. physical maps are based on recombination frequencies

C. genetic maps are based on base pairs

D. None of the above

A

D. None of the above

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2
Q

Which of the following mapping methods has the lowest resolution?

A. Recombination frequency

B. Restriction mapping

C. DNA sequencing

A

A. Recombination frequency

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3
Q

DNA fingerprinting _____.

A. generally employs the polymerase chain reaction

B. is used to identify individual people

C. analyzes short tandem repeats

D. All of the above

E. None of the above

A

D. All of the above

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4
Q

Compared to the original Sanger method of DNA sequencing, next-generation sequencing methodologies _____.

A. have made sequencing faster

B. allow hundreds of thousands to millions of DNA fragments to be simultaneously sequenced

C. Both a and b

D. None of the above

A

C. Both a and b

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5
Q

What is the most likely order of the linked genes R, S, and T if the distance between R and S is 22 m.u., the distance between S and T is 8 m.u., and the distance between R and T is 14 m.u.?
a. RST
b. STR
c.TRS

A

b. STR

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6
Q

From the cross AB/ab x ab/ab, what is the recombination frequency if the progeny numbers are 72 AB/ab, 68 ab/ab, 17 Ab/ab, and 21 aB/ab?
Select an answer and submit.
a. 0.213
b. 0.271
c. 0.500
d. 0.787

A

a. 0.213

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7
Q

An organism that has the haplotypes AB and ab with 12% recombination frequency, what is the % of gametes with ab haplotype?

A

44%

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8
Q

For single crossovers, the frequency of recombinant gametes is half because
a. a testcross between a homozygote and heterozygote produces ½ heterozygous and ½ homozygous progeny.
b. the frequency of recombination is always 50%.
c. each crossover takes place between only two of the four chromatids of a homologous pair.
d. crossovers occur in about 50% of meiosis.

A

c. each crossover takes place between only two of the four chromatids of a homologous pair.

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