Menopause Flashcards

1
Q

Menopause

A

Cessation of menstruation after 12 months of amenorrhea without any pathologic cause

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2
Q

Perimenopause

A

Time of life from the onset of ovarian dysfunction until 1 year after the last menstrual period

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3
Q

Postmenopause

A

1 year since last menstrual period

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4
Q

Age of menopause

A

45- 55 years

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5
Q

Risk factors

A

Iatrogenic causes
Premature ovarian failure
Resistant ovary syndrome

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6
Q

Premature Menopause

A

Before the age of 40 years

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7
Q

Premature ovarian failure features?

A

Elevated FSH and LH
Low Estradiol
Biological appearance of ovary as that of menopausal ovary

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8
Q

Premature ovarian failure causes?

A

Turner syndrome
Enzyme def.
Hypothyroidism
Chemotherapy
Infection
Radiotherapy

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9
Q

Symptoms of menopause?

A

Immediate symptoms (1-5 yr)
Intermediate symptoms (3-10 yrs)
Delayed symtoms (>10 yrs)

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10
Q

Immediate symptoms of menopause

A

hot flushes or night sweats with bad sleep
mood swings
lethargy and lack of energy
depressed mood
changes in memory or cognitive function

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11
Q

Intermediate symptoms of menopause

A

Loss of sexual desire, arousal
Dyspareunia
Urogenital atrophy ( thining of vulva, vaginal dryness, urinary frequency, urgency, nocturia)
Recurrent infections

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12
Q

Delayed symptoms of menopause

A

MI
Stroke
Increased Cholesterol
Decreased HDL
Increased LDL
Normal Triglycerides
Osteoporosis

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13
Q

Management of menopause

A

Lifestyle changes
Non-hormonal Ways
Hormone Replacement Therapy

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14
Q

Lifestyle changes

A

Stop smoking and drinking
Exercise

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15
Q

Vaginal dryness management

A

Pessaries, ring or tablet

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16
Q

If a woman has her uterus removed then what can we give?

A

estrogen

17
Q

Absolute CTDs to HRT

A

Breast CA
Endometrial CA
Active liver disease
Pregnancy if suspected
Uncontrolled HTN
Thromboembolism

18
Q

Relative CTDs of HRT

A

Large uterine fibroids
Benign breast disease
Unconfirmed VTE
Migraine with Aura (give progesterone only)
Chronic stable liver disease