Polycystic Ovarian Syndrome

Question 1

Define PCOS

Answer 1

Syndrome of ovarian dysfunction with hypoandrogenism and cysts

Question 2

Features of PCOS

Answer 2

Hyperandrogenism (Hirsutism, Acne)
Obesity
Irregular menstruation
Acanthosis nigricans

Question 3

Diagnosis of PCOS (LABS) on 2nd day of menses

Answer 3

Increased Testosterone
Increased LH
Increased LH: FSH ratio
Increased fasting insulin levels
Increased Prolactin
Decreased sex hormone binding globulin

Question 4

U/S features of PCOS

Answer 4

12 or >12 follicles in one ovary
Ovarian volume >10 ml

Question 5

Rotterdam Criteria for Dx of PCOS

Answer 5

2 of 3 things
1. Amenorrhea/Oligomenorrhea
2. Hyperandrogenism (Acne, Hirsutism, Alopecia)
3. U/S >12 follicles in one ovary and ovarian volume >10 mL

Question 6

Treatment of PCOS

Answer 6

COCP
Clomiphene Citrate
Metformin
Exercise and Weight loss
Hirsutism treatment

Question 7

What to do for hirsutism

Answer 7

Eflornithine cream
Cyproterone acetate
GnRH agonists
Finasteride
Surgical laser and electrolysis