12 Flashcards

(70 cards)

1
Q

chemoreception

A

when chemicals bind to chemoreceptors and activate action potential in sensory neurons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Gustation

A

Sense of taste

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Olfaction

A

sense of smell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

when odorants reach the mucous layer in the roof of nose they bind to membrane bound receptor proteins, activating

A

olfactory receptor neurons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

axons from these neurons project up to the:

A

olfactory bulb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

part of the brane where olfactory signals are processed and interpreted

A

olfactory bulb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

intracellular peripheral membrane proteins closely associated with trans transmembrane signal receptors

A

G proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

when G proteins are activated by a signal receptor they trigger the production of

A

second messenger

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are second messengers

A

-small, non protein signalling molecule or ion
-links the receipt of an extracellular signal to the production of an intracellular signal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

3 steps of G-protein-coupled signalling

A
  1. a signalling molecule binds to its membrane receptor
  2. the associated G-protein exchanges GDP for GTP and splits into two parts
  3. the active G protein subunit activates a nearby membrane enzyme and catalyzes the production of a second messenger.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

signal transduction in odorant receptors

A
  1. odorant binding to an odorant receptor causes conformational change in the odorant receptor protein
  2. this change in conformation activates G proteins which diffuses through the cytoplasm and activates adenylyl cyclase
  3. adenylyl cyclase converts ATP to cAMP.
  4. cAMP open cAMP gated Na/Ca2+ channels
  5. cAMP gated channels open and sodium and calcium flows in.
  6. calcium opens calcium gated cl channels causing efflux of Cl.
  7. neuron is depolarized
  8. sodium gated channel opens and sodium flows in generating action potential
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

each olfactory receptor neuron expresses __ type of odorant receptor

A

1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

each odorant receptor respond to different odorants with varying affinity.

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

receptors of the same type project to distinct regions in the olfactory bulb called:

A

glomeruli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how does the brain identify specific smells?

A

by interpreting the intensity and pattern of activation of specific glomeruli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

chemicals secreted into the environment and cause a physiological and behavioural change in members of the same species.

A

pheromones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

pheromone receptors are localized in

A

vomeronasal organs (VNO).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

sensory organs in the nasal region of some animals distinct from the olfactory bulb

A

vomeronasal organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

how to calculate the partial pressure of a gas

A

multiple the fractional composition of that gas by the total pressure exerted by the entire mixture.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

pressure of a particular gas in a mixture of gases is called

A

partial pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

it is harder to breathe at high altitudes because

A

the partial gradient between the atmosphere and your lung is small

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

_______ states that the rate of diffusion of a gas depends on 5 parameters

A

Fick’s law of diffusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

the five parameters in fick’s law of diffusion

A
  1. solubility of gas
  2. temperature
  3. surface area for diffusion
  4. differences in partial pressures across the gas exchange surface
  5. thickness of the barrier in diffusion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Rate of diffusion =
k x A x (P2 - P1)/D k = diffusion constant A = area for gas exchange D = distance of diffusion
26
Five major steps of gas exchange
1. Ventilation 2. diffusion at the respiratory surface 3. Circulation 4. Diffusion at the tissues 5. Cellular respiration
27
ventilation
movement of air through a specialized gas exchange organ
28
Diffusion at the respiratory surface
where oxygen moves from the air or water into the blood and CO2 moves from the blood into the air or water.
29
Circulation
transport of dissolved CO2 and O2 throughout the body via the circulatory system
30
Diffusion at the tissues
O2 moves from blood into tissues and CO2 moves out if the tissues into blood.
31
Cellular respiration.
the cell’s use of O2 to produce co2. leads to high Co2 and low o2 levels in the tissues
32
respiratory system
collection of cells, tissues, and organs responsible for gas exchange.
33
34
ram ventilation
when fish force water through their gills by opening their mouths
35
the stiff flap over fish gills is called
operculum
36
most fish ventilate by
opening and closing their mouths and operculum to create a pressure gradient
37
structure of gill
gill filaments extend from each gill arch and each gill arch contains thousands of sheet like gill lamellae
38
structure of lung in the order that each component branches out
Trachea bronchi bronchioles alveoli
39
alveoli consists of (from the air side to the blood side)
- a thin aqueous film - epithelium of alveolus - extracellular matrix material(ECM) - the wall of a capillary
40
humans ventilate their lungs by
changing pressure within their chest cavity.
41
change in volume of lung is caused by a downward motion of a thin muscular sheet called the:
diaphragm
42
each lung is surrounded by a pleural sac which is composed of
two layers of cells with small space between them
43
inhalation
during inhalation, the diaphragm moves down and the pressure in the chest cavity is lowered, causing the lungs to expand and air to move in.
44
exhalation
as diaphragm relaxes, the chest cavity volume decreases, and air is exhaled. - passive process driven by the elastic recoil of the lungs and chest wall as the diaphragm and rib muscle relax. - it can become energy demanding during exercise
45
functions of brain stem
information relay, autonomic control of the heart, lungs, digestive system.
46
the mammalian rate of breathing is controlled by the
medullary respiratory centre
47
how does the body deal with increased CO2 conc
Increased CO2 react with water in the blood and cerebrospinal fluid to form carbonic acid H2CO3, which dissociates in to H+ and bicabonate ion HCO3. the release of hydrogen ions lowers the blood and CSF pH, which is sensed by specialized chemoreceptors which stimulate CNS control centers to increase breathing rate.
48
blood is a fluid connective tissue consisting of cells in a watery extracellular matrix called:
plasma
49
the blood is composed of
plasma platelets white blood cells red blood cells
50
Platelets
cell fragments that minimize blood loss.
51
white blood cells
part of the immune system
52
red blood cells
transport of CO2 and O2
53
red blood cells contain an oxygen carrying molecule called
hemoglobin
54
composed of four polypeptide chains, each of which binds to a non protein group called heme
hemoglobin
55
each heme contains an iron ion that can bind to an
oxygen molecule
56
the oxygen-hemoglobin equilibrium curve plots the
percentage saturation of hemoglobin vs the partial pressure of oxygen in tissues
57
decreases in pH alter hemoglobins conformation and causes a ___ shift in the hemoglobin curve
right
58
temperature increase decrease oxygen affinity and causes a _____ shift
right
59
fetal hemoglobin has a higher affinity for oxygen than adult hemoglobin therefore
more oxygen is needed to supply tissues
60
______ _______ in red blood cells catalyzes the formation of carbonic acid from carbon dioxide in water.
carbonic anhydrase
61
CO2 that diffuses into red blood cells is converted to
bicarbonate ions and protons.
62
most CO2 is transported in blood in the form of
bicarbonate ions
63
parietal cells have a high concentration of the enzyme _____ ______ and ______
carbonic anhydrase, mitochondria
64
where is carbonic anhydrase found?
in red blood cells
65
importance of red blood cells for two reasons
1. the protons produced by the carbonic anhydrase reaction induce the Bohr shift, which makes hemoglobin more likely to release oxygen. 2. the Pco2 in blood drops when CO2 is converted to bicarbonate, favouring entry of CO2 into red blood cells
66
proton generated from the conversion of co2 to bicarbonate binds to ______
hemoglobin
67
diffusion of CO2 out of the alveoli
1. hydrogen ions leave their binding sites on hemoglobin 2. hydrogen ions react with bicabonate to form CO2 3. CO2 diffuses into the alveoli anf is exhaled from the lungs
68
reactions to synthesize HCO3 occur in the:
RBC
69
HCO is exchanged for Cl in the plasma at the ____
tissues
70
Cl is exchanged for HCO3 in the plasma at the ____
alveoli