12 Flashcards
(70 cards)
chemoreception
when chemicals bind to chemoreceptors and activate action potential in sensory neurons
Gustation
Sense of taste
Olfaction
sense of smell
when odorants reach the mucous layer in the roof of nose they bind to membrane bound receptor proteins, activating
olfactory receptor neurons
axons from these neurons project up to the:
olfactory bulb
part of the brane where olfactory signals are processed and interpreted
olfactory bulb
intracellular peripheral membrane proteins closely associated with trans transmembrane signal receptors
G proteins
when G proteins are activated by a signal receptor they trigger the production of
second messenger
what are second messengers
-small, non protein signalling molecule or ion
-links the receipt of an extracellular signal to the production of an intracellular signal
3 steps of G-protein-coupled signalling
- a signalling molecule binds to its membrane receptor
- the associated G-protein exchanges GDP for GTP and splits into two parts
- the active G protein subunit activates a nearby membrane enzyme and catalyzes the production of a second messenger.
signal transduction in odorant receptors
- odorant binding to an odorant receptor causes conformational change in the odorant receptor protein
- this change in conformation activates G proteins which diffuses through the cytoplasm and activates adenylyl cyclase
- adenylyl cyclase converts ATP to cAMP.
- cAMP open cAMP gated Na/Ca2+ channels
- cAMP gated channels open and sodium and calcium flows in.
- calcium opens calcium gated cl channels causing efflux of Cl.
- neuron is depolarized
- sodium gated channel opens and sodium flows in generating action potential
each olfactory receptor neuron expresses __ type of odorant receptor
1
each odorant receptor respond to different odorants with varying affinity.
true
receptors of the same type project to distinct regions in the olfactory bulb called:
glomeruli
how does the brain identify specific smells?
by interpreting the intensity and pattern of activation of specific glomeruli
chemicals secreted into the environment and cause a physiological and behavioural change in members of the same species.
pheromones
pheromone receptors are localized in
vomeronasal organs (VNO).
sensory organs in the nasal region of some animals distinct from the olfactory bulb
vomeronasal organs
how to calculate the partial pressure of a gas
multiple the fractional composition of that gas by the total pressure exerted by the entire mixture.
pressure of a particular gas in a mixture of gases is called
partial pressure
it is harder to breathe at high altitudes because
the partial gradient between the atmosphere and your lung is small
_______ states that the rate of diffusion of a gas depends on 5 parameters
Fick’s law of diffusion
the five parameters in fick’s law of diffusion
- solubility of gas
- temperature
- surface area for diffusion
- differences in partial pressures across the gas exchange surface
- thickness of the barrier in diffusion