12 Flashcards
(22 cards)
presentation primary HIV/ seroconversion
abrupt onset
- flu-like
- fever
- malaise
- lethargy
- pharyngitis
- lymphadenopathy
- toxic exanthoma
management chronic hep B infection
to treat if symptomatic without cirrhosis need 2/3 of:
- > HBV DNA
- raised ALT
- significant inflammation/ fibrosis
define septic shock
sepsis with persisting hypotension requiring vasopressors requiring vasopressors to maintain MAP >65mmHg
+
serum lactate >2mmol/l despite adequate volume resus
describe linezolid as an antibiotic in staph aureus infection
- bacteriostatic
- synthetic oxazolidinone
- good penetration into bone
- excellent bioavailability
describe pseudomembranous colitis
swelling or inflammation of the large intestine due to c.diff overgrowth
what is the malaria vector
female anopheles mosquito
presentation of neuroborreliosis
triad:
- facial nerve palsy
- radicular pain
- lymphocytic meningitis
onset of symptoms 2-6 weeks after bite
potential complications of malaria
- cerebral malaria
- blackwater fever
- pulmonary oedema
- jaundice
- severe anaemia
- gram negative septicaemia
presentation acute acrodermatitis chronica atroficans
affects extensor surfaces of distal extremities
bluish-red discolouration
peripheral neuropathy
cause of erythema migrans
Lyme disease
precautions that should be taken with c.diff patient
- wash hands with soap and water
- isolation
- PPE
- clean environment
management c.diff infection if no severity markers
- stop unnecessary antibiotics
- rehydrate
oral metronidazole
management c.diff infection if >2 severity markers
- stop unnecessary antibiotics
- rehydrate
oral vancomycin
management lyme borrelios
- oral doxycycline/ amoxicillin
- IV ceftriaxone
- treat for 21 days
management leptospirosis
- doxycycline for mild disease
- IV penicillin for severe
- prompt dialysis
- mechanical ventilation
where would you find clostridium pefringens
undercooked meat/ cooked foods left out
when do HEV symptoms occur
more than 40 days incubation
define sepsis
life threatening organ dysfunction caused by dysregulated host response to infection
sepsis ‘take 3’
- blood cultures
- blood lactate
- urine output
management large areas of impetigo
topical and oral antibiotics e.g. flucloxacillin
presentation impetigo
multiple vesicular lesions on an erythematous base
golden crust is highly suggestive of this diagnosis
PJP investigations
- CD4 count
- FBC
- CXR
- induced sputum or bronchoscopy for PCR
