6

Question 1

management of subacute innvasive aspergillosis, aspergilloma and mucocutaneous candidiasis

Answer 1

• amphotericin B formulations
• azoles
• echinocandins
• flucytosine

Question 2

leptospirosis investigations

Answer 2

• blood culture
• PCR
• ELISA
• microscopic agglutination test

Question 3

pyrexia of unknown origin

Answer 3

persisting fever with unknown cause

Question 4

staphylococcal toxic shock syndrome

Presentation

Answer 4

• fever
• hypotension
• abdo/ pelvic pain
• diffuse macular rash
  involvement of 3 of the following:
  1. liver
  2. blood
  3. renal
  4. GI
  5. CNS
  6. MSK

Question 5

presentation panton-valentine leucodin toxin

Answer 5

recurrent boils which are difficult to treat

Question 6

epidemiology of campylobacter gastroenteritis

Answer 6

commonest bacterial food poisoning in UK

chicken/ contaminated milk/ puppies

isolated causes not outbreaks

Question 7

management surgical site infection

Answer 7

consider unlikely pathogens as cause if obtained from a normally sterile site
antibiotics to target likely organism

Question 8

define impetigo

Answer 8

superficial skin infection only infecting epidermis

highly infectious

Question 9

typhoid investigations

Answer 9

• culture of blood, urine, stool and bone marrow

Question 10

management seasonal flu

Answer 10

neuraminidase inhibitors ASAP
oseltamivir
zanamivir

Question 11

complications typhoid fever

Answer 11

• intestinal bleeding
• perforation
• peritoneum
• metastatic infections

Question 12

what causes an influenza pandemic

Answer 12

antigenic shift

Question 13

presentation folliculitis

Answer 13

circumscribed, pustular infection of a single hair follicle
constitutional symptoms not often seen
small red papule
head/ back/ buttocks + extremities

Question 14

risk factors for surgical site infections

Answer 14

• diabetes
• smoking
• obesity
• malnutrition
• concurrent steroid use
• colonisation with staph aureus

Question 15

if a traveller returned with enlarged lymph nodes, consider

Answer 15

• leishmania

- trypanosomiasis

Question 16

management invasive candidiasis

Answer 16

echinocandins and fluconazole

Question 17

function neuraminidope

Answer 17

enables new iron to be released from host cell

Question 18

chronic hep B infection investigations

Answer 18

• HBsAb
• HBeAg
• anti HBc

Question 19

what does SIRS stand for

Answer 19

systemic inflammatory response syndrome

Question 20

define rabies

Answer 20

viral infection transmitted from the bite of an infected animal

Question 21

define staphylococcal scalded skin syndrome

Answer 21

infection due to particular strain of staph aureus which produces the exfoliative toxin A or B

Question 22

what is shigella

Answer 22

bacteria closely related to e.coli