2.2.1 Escherichia coli

Question 1

Who isolated E. coli?

Answer 1

Theodore Escherich 1885

Question 2

E. coli is considered as colon Biota?

Answer 2

Yes since it is normal flora of it

Question 3

What does E. coli posses?

Answer 3

Adhesive fimbriae and sex pili

Question 4

What antigenic structure does E. coli has?

Answer 4

K (K1 antigen)
O (Similar to Shigella)
H

Question 5

O antigen cross reactivity of E. coli is done with what spp. of Enterobacteriaceae

Answer 5

Shigella

Question 6

What Bacteria has a Similar K1 antigen with E. coli?

Answer 6

Neisseria meningitidis

Question 7

What are the diseases of E. coli?

Answer 7

UTI
Neonatal meningitidis
Diarrheal syndrome
Gram negative sepsis (Mostly E. coli)
Nosocomial wound

Question 8

What diseases in E. coli is the most common cause of infection ?

Answer 8

UTI

Question 9

What are the virulence factor that can cause UTI?

Answer 9

Pili = adhesion
Cytolysins = Inhibit immune effector cells

Aerobactin = Chelates iron (Similar to Nocobactin) for multiplication of bacteria

Question 10

What bacteria causes UTI?

Answer 10

1. E. coli
2. Proteus
3. S. saprophyticus

Question 11

What bacteria is the leading cause of neonatal meningitis?

Answer 11

Streptococcus agalactiae

Question 12

In LIA, what are the Reagents?

Answer 12

Lysine decarboxylase