Plasmodium Lecture Flashcards

1
Q

by means of which they attach to and penetrate host cells

A

apical complex

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2
Q

The medically important parasites in this group are the

A

Malaria parasites
Coccidia
Babesia

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3
Q

Parasite that is most in the Philippines

A

Plasmodium falciparum

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4
Q

Parasite that is most common in the World

A

Plasmodium vivax

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5
Q

The name malaria (mal:_____ , aria: ____)

A

bad, air

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6
Q

The name malaria was given in the ______ in ______

A

18th century, Italy

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7
Q

He discovered the specific agent of malaria. What year?

A

Alphonse Laveran,1880

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8
Q

He described the asexual development of the parasite in RBCs

A

Golgi, 1886

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9
Q

He developed a method of staining malarial parasites in blood films

A

Romanowsky in Russia ,1891

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10
Q

What are the different species of malaria parasite infecting man

A

Plasmodium vivax
Plasmodium malariae
Plasmodium falciparum

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11
Q

Where and when does the malaria species occur?

A

Italy, 1886 & 1890

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12
Q

What is the 4th species that identified in 1992

A

Plasmodium ovale

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13
Q

Who established the Mode of Transmission?

A

Ronald Ross ,1897

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14
Q

Primary Mosquito Vector

A

Anopheles flavirostris

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15
Q

Secondary Mosquito Vector

A

Anopheles litoralis
Anopheles maculatus
Anopheles mangyanus
Anopheles balabcensis

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16
Q

What are the Host resistance of Plasmodium

A

Duffy negative red blood cells
Nature of Hgb
G6PD deficiency
HLA(Human Leukocyte Antigen)-B53
Pregnancy
Splenectomy

17
Q

What are the Hemoglobin are used in Host resistance

A

HbE
HbS
HbF-neonates

18
Q

In MOT, it is accidentaly transmit malaria

A

Transfussion malaria

19
Q

In MOT, it is transmitted transplacentally mother to fetus

A

Congenital Malaria

20
Q

In MOT, Shared syringes may be responsible

A

Malaria in Drug Addicts

21
Q

In MOT, the donor had parasitemia

A

Renal Transplantation

22
Q

It is the most common species in tropical parts of the world

A

Plasmodium falciparum

23
Q

found in the tropics, subtropics, and some temperate areas of the world

A

Plasmodium vivax

24
Q

It is less common but is found in much of the tropical world

A

Plasmodium malariae

25
Q

It is considered a rare species. It is relatively common in West Africa, India, and South America

A

Plasmodium ovale

26
Q

What are the treatment that most commonly used in plasmodium spp:

A

Chloroquine
Amodiaquine
Quinine
Pyrimethamine
Doxycycline
Sulfadoxine
Proguanil
Primaquine

27
Q

Prodromal Stage

A

fever
Body malaise
headache

28
Q

Duration of Primary Clinical Malaria

A

P. vivax: 3-8+ weeks
P. ovale: 2-3 weeks
P.malariae: 3-24 weeks
P. falciparum: 2-3 weeks

29
Q

Duration of untreated malaria

A

P. vivax: 5-7 years
P. ovale: 10 months
P. malariae: +20 yrs
P. falciparum: 6-17 months

30
Q

Signs & Symptoms:
II. Stage of Active Invasion

A

Anemia
Hepatosplenomegaly

31
Q

Signs & Symptoms:
III. FEBRILE PAROXYSMS (6-10H)

A

Cold stage: 20mins - 1hr
Hot stage: 1-4 hrs
Sweating stage: 2-3hrs

32
Q

Incubation Periods:

A

P. vivax: 12-20 days
P. ovale: 11-16 days
P. malariae: 18-40 days
P. falciparum: 8-15 days