Cutaneous manifestatios of Diseases

Question 1

Clinical features of tuberous sclerosis

Answer 1

Angiofibromas, ashleaf macules, shagreen patch, Ungal fibromas

Question 2

What are angiofibromas

Answer 2

Dome-shaped, firm papules in a butterfly distribution across the face

Question 3

What are ashleaf macules

Answer 3

Oval patches of white/hypopigmented skin

Question 4

What are shagreen patches

Answer 4

Leathery plaques on the sacrum that is dimpled like orange peel

Question 5

What are ungal fibromas

Answer 5

Smooth, fleshy tumours that grow from the nail folds either around the nail or under the nail

Question 6

Features of Type 1 Neurofibromatosis

Answer 6

Cafe-au-lait spots, axillary or inguinal freckling and neurofibromas (small nodular tumours in skin)

Question 7

Clinical features of Porphyria cutanea tarda

Answer 7

Photosensitivity which often affects dorsum of hands, causing blister/bullae formation which easily rupture to form erosions. Also hyperpigmentation and hypertrichosis

Question 8

Clinical features of systemic sclerosis

Answer 8

Raynaulds, sclerodactyly, scleroderma affecting face and hands, telangiectasia

Question 9

Clinical features of SLE

Answer 9

Photosensitivity (malar rash), discoid rash, mouth/nose/genital ulcers, hair loss, cutaneous vasculitis