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CC Flashcards

1
Q

True of cholesterol metabolism, except

A. free cholesterol is the inactive form of
cholesterol with cytotoxic property
B. Free cholesterol and phospholipids
have a hydrophilic property
C. both have hydrophilic and
hydrophobic properties
D. the process of esterification is a
“detoxification” step cholesterol ester
is almost 90% in plasma

A

B. Free cholesterol and phospholipids
have a hydrophilic property

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2
Q

It is the recommended fasting hour in
most clinical biochemistry tests: 6-8 hours

A

8-12 hours

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3
Q

True of R4s, except:

A. it is caused by random errors
B. it is observed after 2 consecutive
days
C. R means random error
D. difference between the highest and
lowest control result exceeds 4s

A

B. it is observed after 2 consecutive
days

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4
Q

It is the ideal reference limit:

A

2s

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5
Q

It is the most abundant lipid in human
plasma:

A

Cholesterol

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6
Q

True of creatinine, except:

A. a measure of the completeness of
24-hour urine collection
B. plasma creatinine may not be
increased until renal function has
deteriorated more than 50% plasma
creatinine is usually within the
reference limit in muscular diseases
C. in muscular dystrophy, plasma
creatine is decreased while urinary
creatinine is elevated

A

C. in muscular dystrophy, plasma
creatine is decreased while urinary
creatinine is elevated

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7
Q

Control values are computed based on: 1.mean
2. median
3. standard deviation
4.variance

A

1 and 3

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8
Q

if urea is the most abundant NPN in
plasma, ______________ is the least in concentration. creatine

A

Ammonia

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9
Q

Safety glasses, face shields or other eye
protectors must be worn when:

A

working with toxic materials

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10
Q

Observable symptoms of hypoglycemia can be observed when plasma glucose reach this level

A

plasma glucose level ≤55 mg/dL (3.0
mmol/L);

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11
Q

It is a subset of molecular luminescence
spectrometry and measures the amount of light intensity present over a zero
background:

A

Fluorometry

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12
Q

This method is based on the measurement f scattered light and is ideal for quantitative analysis of immunoglobulins:

A

Nephelometry

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13
Q

Serum urea levels drop in severe hepatic diseases, therefore, low BUN is not generally considered abnormal renal function

A

only the second is correct

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14
Q

True of diagnostic specificity, except

A

it generates more true-positive
results

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15
Q

Primary function of serum albumin in the peripheral blood is to

A

maintain colloidal osmotic
pressure

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16
Q

True of the ion-selective electrode, except

A

indirect ISE requires sample
dilution

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17
Q

It refers to the closeness of assayed values

A

Precision

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18
Q

It is known as the rapid serum tube
since clotting of blood would take
place within 5 minutes: pearl white
top

A

Orange top

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19
Q

This hormone which is released from the islet cells of the pancreas inhibits insulin

A

Glucagon

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20
Q

It is the reference method in the
determination of lipoproteins:

A

ultracentrifugation

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21
Q

Before an OGTT is performed, which of the following should be observed?

A

patient should have consumed at least 150 grams/day of carbohydrates for 3 days prior to testing

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22
Q

is the reference method in the
measurement of renal NPNs:

A

IDMS notsure

23
Q

It is the only protein with enzymatic activity

A

transferrin

24
Q

Earliest NPN to rise in plasma in cases of
kidney diseases:

A

Urea

25
Q

Uniform turbidity in the refrigerated serum indicates elevated concentrations of lipoprotein and lipid:

A

pre-beta lipoprotein and
endogenous triglyceride

26
Q

When serum is mixed with the alkaline
picrate reagent and the rate of change in absorbance is measured between 2 points, how do you explain this assay?

A

Kinetic Jaffe method

27
Q

To avoid interferences caused by biotin
in immunoassays, blood should be
drawn only after how many hours of not
taking that supplement.

A

48 hours

28
Q

The following are the diagnostic criteria
for diabetes mellitus, except:

A

Point-of-care assay of greater
than or equal to 140 mg/dL

29
Q

It determines the components of a
sample where the x-axis represents
the mass-to-charge (m/z) ratio and the
y-axis is their relative abundance within
the sample:

A

mass specrometry

30
Q

It is a gestational marker that is
increased in anencephaly and spina
bifida:

A

AFP rev

31
Q

This inflammatory protein marker and APR is included in the biomarkers for COVID-19 due to its reaction to cytokine storm

A

CRP

32
Q

In electrophoresis, A high ionic
strength prevents effective separation
of electrophoretic bands while
migration of proteins is inversely
proportional to molecular size:

A

both statements are correct

33
Q

These are vital tests in assessing
individuals who are at risk of
developing coronary artery disease:
1. cholesterol
2. triglycerides
3. phospholipids
4. fatty acids

A

cholesterol and triglycerides

34
Q

Which of the following is the best choice for decontaminating bench tops spilled with body fluid?

A

10% sodium hypochlorite

35
Q

In external quality control testing, unknown samples should be processed and treated like a patient sample while the results of the proficiency testing may be shared with other diagnostic laboratories during the period of analysis:

A

only the first statement is correct

36
Q

It is the recommended fasting hour in
most clinical biochemistry tests:

A

8-12 hours

37
Q

It is described as the chemically
cleaned test tube that is designed for
the analysis of trace elements:

A

royal blue top

38
Q

What is the most common cause of
trend?

A

deterioration of reagent

39
Q

How long do we store the saved/processed serum in Chemistry?

A

7 days

40
Q

What is the main machine/analyer used
in Chemistry?

A

Dimension EXL 200

41
Q

Machine used for Micral test
(Microalbumin Test) and HbA1c

A

DCA Vantage

42
Q

bad cholesterol

A

LDL

43
Q

good cholesterol

A

HDL

44
Q

chemical determinations may be of help in establishing the presence of seminal
fluid?

A

Acid phosphatase (ACP)

45
Q

. A hospitalized patient is experiencing
increased neuromuscular irritability
(tetany). Which of the following tests
should be ordered immediately?

A

Calcium

46
Q

Analysis of CSF for oligoclonal bands
is used to screen for which of the
following disease states?

A

Multiple sclerosis

47
Q

When myocardial infarction occurs,
the first enzyme to become elevated is

A

CK

48
Q

The preparation of a patient for
standard glucose tolerance testing
should include

A

High carbohydrate diet for 3 days

49
Q

A critical ill patient becomes
comatose. The physician believes the
coma is due to hepatic failure. The
assay most helpful in this diagnosis is:

A

Ammonia

50
Q

What enzyme catalyzes the
conjugation of bilirubin?

A

Uridine diphosphate glucoronyltranferase

51
Q

What is the anticoagulant of choice
for blood gas examination?

A

Heparin

52
Q

The nitrogenous waste product of
nucleic acid or purine metabolism is:

A

Uric acid

53
Q

Clearance test for urea and
creatinine measure:

A

GFR

SJ (8 decks)

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