peptic ulcer disease & hyperacidity

Question 1

• chemical compounds that buffer/neutralize hydrochloric acid in stomach, thereby increase gastric pH
• relieves symptoms, doesn’t promote ulcer healing
• AE: constipation, diarrhea, sodium & water retention
• hypermagnesemia

Answer 1

antacids

Question 2

teach patients to take antacids at least ___ hours before any other medications

Answer 2

2

Question 3

when taking antacids, avoid _____ or _____ foods as well as ________

Answer 3

spicy, greasy, alcohol

Question 4

• decrease acid secretion
• AE: diarrhea, dizziness, drowsiness, headache
• can be taken with/without food
• usually admin on scheduled basis

Answer 4

cimetidine & famotidine

Question 5

cimetidine & famotidine are:

Answer 5

histamine2 receptor antagonists

Question 6

omeprazole is a

Answer 6

proton pump inhibitor (PPI)

Question 7

• strong inhibitor gastric secretion
• more effective in preventing secretion, have longer duration of action
• AE: nausea, diarrhea, headache, increased risk bone fracture (prolonged use)
• don’t chew/crush
• take 30min prior to eating, typically at breakfast

Answer 7

omeprazole

Question 8

• prevent & treat peptic ulcer disease
• has mucosal protection, forming a protective barrier by binding to normal & ulcerated mucosa
• AE: constipation, dry mouth
• take other drugs 30min before/after

Answer 8

sucralfate (Carafate)

Question 9

teach pt to take sucralfate __ times daily at bedtime for active ulcers & __ times daily for maintenance

Answer 9

4, 2