pain, fever, & inflammation Flashcards

1
Q
  • doesn’t treat inflammation
  • reduces fever & decreases minor pain
  • 4grams max over 24h
  • duration 3-4h
  • AE: hepatotoxicity, renal failure
  • CI alcohol & hepatic impairment
A

acetaminophen

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2
Q

what is treatment for OC acetaminophen?

A

acetylcysteine

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3
Q
  • relieves pain, reduces fever
  • diminish inflammation by blocking prostaglandins
  • suppress platelet aggregation
  • risk for bleeding
A

aspirin

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4
Q

if aspirin is given to children, what can occur?

A

reye’s syndrome

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5
Q
  • relieve mild to moderate pain such as dysmenorrhea
  • treat inflammation related to RA and OA
  • can take w/ food/liquid to decrease gastric irritation
  • older adults w/ high use are at risk for bleeding
  • can worsen/cause kidney impairment
A

ibuprofen

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6
Q
  • mild to moderate pain (dysmenorrhea)
  • longer acting (12h)
  • more likely to have GI side effects
A

naproxen sodium (Aleve)

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7
Q
  • relieves pain associated w/ RA< OA, ankylosing spondylitis, bursitis, tendonitis, & gouty arthritis
  • use only in acute gout attacks
  • BEERs list
  • assess for CNS, GI, cardiac bleeding effects
A

ketorolac

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8
Q

cardinal s/s inflammation include

A

pain, fever, redness, swelling, malaise, drainage of exudate

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9
Q

fever

A

100.4

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10
Q
  • produces joint pain inflammation & degernation
  • Tx aspirin, acetaminophen, NSAIDs
A

osteoarthritis

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11
Q
  • overproduction uric acid
  • causes tophi, enlarged joint, pain/swelling
  • Tx NSAID, corticosteroid
A

gout

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12
Q
  • short-term Tx inflammatory disorders
  • doesn’t cure disease
  • AE: HTN, hyperglycemia, immunosuppression, impaired healing, mood changes, wt gain , sodium/fluid retention
  • CI live vaccine use
  • must be tapered off
A

prednisone & methylprednisolone sodium succinate

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13
Q

what time should steroids be given?

A

0900 to mimic peak diurnal concentration

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14
Q

T/F: grapefruit juice can be given with antigout medication

A

F

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15
Q
  • adrenal insufficiency
  • not enough cortisol —> hypotension
A

addison’s disease

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16
Q
  • exhausted body stores of glucocorticoids in a pt w/ adrenal insufficiency after trauma, surgery, or other –> can lead to shock
A

addisonian crisis

17
Q
  • key hormone in RAAS system & stress response
  • increases BP, HR
  • stimulates retention fluid & sodium
  • deficiency causes increases renal sodium loss & enhances potassium reabsorption –> BP drop due to loss of sodium
A

alosterone

18
Q
  • excess cortisol production & circulation in bodu
  • can lead to adrenal crisus
A

cushing’s disease

19
Q
  • lipid soluble hormones
A

glucocorticoid

20
Q
  • affect every aspect of inflammatory & immune responses
  • important in hemostasis & metabolic processes
  • suppress severe inflammation
  • secretion controlled by hypothalamus
A

corticosteroid