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Adrenergic Pharmacology > Salbutamol - Beta 2 agonist > Flashcards

Salbutamol - Beta 2 agonist Flashcards

1
Q

MOA

A

Beta-2 receptor agonist. Acts a bronchodilator. It decreases calcium-mediated contraction of the bronchioles by increasing cAMP which activates PKA. PKA inhibits MLCK preventing contraction

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2
Q

Abs/Distrb/Elim

A

InhalationGiven IV
Short acting 3-5hrs

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3
Q

Clinical use

A

Asthma
COPD

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4
Q

Adverse effects

A

Tremors
Tachycardia
Fall in bp

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Adrenergic Pharmacology (4 decks)

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