DNA Structure Flashcards

1
Q

what is DNA

A
  • a type of nucleic acid
  • a macromolecule containing genetic info
  • in eukaryotic cells it is found in the nucleus
  • in prokaryotic cells it is found in the cytoplasm
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2
Q

what are nucleic acids

A

polymers

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3
Q

what are DNA monomers called

A
  • nucleotides
  • many monomers bonded together are called polynucleotide
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4
Q

what are nucleotides made of

A
  1. a phosphate group
  2. pentose sugar
  3. a nitrogenous base
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5
Q

what are the two types of pentose sugars

A
  • deoxyribose (missing an O2 atom)
  • ribose (has missing O2 atom)
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6
Q

how many nitrogenous bases are there and what are they called

A
  • 4 types
  • adenine bonds to thymine
  • guanine bonds to cytosine
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7
Q

what is the phosphodiester bonds

A

the phosphate group bonded to the pentose sugar

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8
Q

what does the phosphodiester bond create

A

a sugar-phosphate backbone

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9
Q

how are polynucleotides read

A

read from 5’ to 3’

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10
Q

DNA polymers

A
  • double stranded
  • two strands are antiparallel and complementary
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11
Q

what are the two strands held together by

A
  • hydrogen bonds which forms the double helix shape
  • hydrogen bond holds the two strands together like a zipper
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12
Q

what does antiparallel mean

A
  • one strand of the backbone runs from 5’ - 3’
  • second stand runs from 3’ - 5’
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13
Q

what does complementary mean

A
  • nitrogenous bases on one strand are complementary to bases on the other strand
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14
Q

how many bonds does each nitrogenous base form

A
  • adenine forms 2 hydrogen bonds with thymine
  • guanine forms 3 hydrogen bonds with cytosine
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15
Q

how is the double helix formed

A
  • phosphodiester bonds form backbone of the DNA ladder
  • hydrogen bonds are the rungs of the ladder
  • when it is twisted it forms the double helix shape
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16
Q

how does polynucleotide become chromosome

A
  • DNA double helix coils around proteins called histones to form nucleosomes
  • DNA is called chromatin at this point
  • chromatin coils and supercoils to form a chromosome
17
Q

how does one chromosome form

A
  • double helix condenses to form a single chromosome (unduplicated)
  • chromatid replicates (during S-phase of interphase) to form sister chromatid
  • still one chromosome but is duplicated
  • splits during mitosis and one chromatid goes to each daughter cell