gram negative Flashcards

1
Q

what are the 4 main groups of gram negative bacteria?

A

Proteobacteria

Bacteroids

Chlamydias

Spirochaetes

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2
Q

what shape are proteobacteria

A

rod (bacilli)

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3
Q

what shape are bacteroids

A

rod (bacilli)

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4
Q

what shape are chlamydias

A

round pleimorphic

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5
Q

what shape are Spirochaetes

A

spiral

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6
Q

what family does enterobacteria belong to?

(these are commonly encountered pathogens)

A

proteobacteria

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7
Q

what are features of the enterobacteria?

A
  • bacilli
  • most are motile
  • Facultatively anaerobic - ie. they can grown anaerobically if necessary
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8
Q

what are the 3 main examples of enterobacteria ?

A

E.Coli

Shigella

salmonella

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9
Q

E.coli

  • features
A

Commensal bacteria

Most abundant facultative anaerobic bacteria in gut

Has peritrichous flagella

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10
Q

E.coli

what infections can it cause?

A

wound infections eg. following surgery
cystitis (UTIs)
gastroenteritis
‘traveller’s diarrhoea’
Can lead to sepsis
Rare cause of meningitis in infants

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11
Q

shigella

what infections does It cause?

A

Causes shigellosis infections (bacillary dysentery, severe bloody diarrhoea)

symptoms -

Frequent pass of stools of small volume
Pus and blood, cramps and pain in straining
Fever

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12
Q

shigella

features that make it effective

A
  • shiva toxin
  • acid tolerant
  • induces apoptosis in macrophages
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13
Q

salmonella

what are the 3 forms of salmonellaosis infection?

A

Gastroenteritis/enterocolitis( from food poisoning)

Enteric fever aka. typhoid (from poor water quality)

Bacteraemia

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14
Q

BACTEROIDS

  • are they aerobic or anaerobic?
  • are the commensal flora?
A

anaerobic

commensal flora in large intestine

opportunistic to tissue injury

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15
Q

CHLAMYDIA

  • how do you test for it?
A

PCR

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16
Q

CHLAMYDIA

  • what are the 2 uniques stages of its life cycle
A

Elementary bodies form - rigid, infectious

Reticulate bodies form - fragile, non-infectious

17
Q

SPIROCHAETES

  • are they mostly pathogenic or non?
  • what is their key feature (other than spiral shape)
A

most are free-living and non-pathogenic

endofagella to propel in corkscrew motion

18
Q

what are the 3 medially important spirochetes?

A

Borrelia burgdorferi → Lyme disease

Leptospira interrogans → leptospirosis

Treponema pallidum → syphilis (STD)

19
Q

all prteobacteria are rod shaped bar 2 exceptions? what are these

A

Neisseria (diplococci)
and the Campylobacter/Helicobacter genera (spiral)