Idt 5 Flashcards

1
Q

Ergots target what

A

5HT partial agonist
D2/D3 partial agonist

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2
Q

How is sumatriptan metabolized and what does this mean for DDI

A

MAOA
Do not take with MAOI

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3
Q

Which triptans can be taken with MAOI and why

A

Naratriptan
Frovatriptan
Eletriptan
Amine-ring blocks MAOA

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4
Q

Which triptan has half life of over a day?

A

Frova

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5
Q

Gepants should not be taken with what

A

3A4 inhibitor or inducers

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6
Q

Gepants MOA

A

CGRP receptor antagonist

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7
Q

Gepants should have what in order to resemble what

A

Amide linkages
To resemble peptide bonds

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8
Q

Which triptans are odt

A

Riza
Zolmi

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9
Q

Nasal triptans

A

Suma
Zolmi

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10
Q

Which triptans have delayed onset

A

Frova
Nara

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11
Q

Ergot alkaloids must be used along with

A

Antiemetics
Chlorpromazine
Prochlorpromazine
Metoclopramide

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12
Q

Why is lasmiditan safe in CVD

A

Lacks vasoconstriction

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13
Q

Lasmiditan often causes

A

Dizziness and drowsiness

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14
Q

Migraines and COCs

A

Should be avoided
The dose is lower now
But progestin only birth control is available

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15
Q

Cluster headache can be treated with

A

O2
SSRI
Triptan nasal or IV

IN lidocaine if triptan CI

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16
Q

Cluster headache preventive

A

Verapamil
Lithium