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MP322 > Management of GORD and peptic ulcers > Flashcards

Management of GORD and peptic ulcers Flashcards

1
Q

Alginates

A

Peptac
Gaviscon (rafting agents)

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2
Q

Antacids

A

Co-magaldrox
Magnesium Trisilicate

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3
Q

PPIs

A

Omeprazole (10mg, 20mg, 40mg)
Lansoprazole (15mg, 30mg)
Esomeprazole (20mg, 40mg) Pantoprazole (20mg, 40mg)
Rabeprazole (10mg, 20mg)

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4
Q

PPI dosage forms

A

Tablets
Capsules
Granules
Dispersible tablets
Oral liquids
Injections

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5
Q

PPI cautions

A

Risk of bone fracture for prolonged use
Increased C. diff
Mask cancer symtoms
Rebound hyper-secretion of acid

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6
Q

PPI side interactions

A

Omeprazole & Esomprezaole decrease antiplatelet effect of clopidogrel

Pantoprazole increases anticoagulant effect of warfarins

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7
Q

PPI side effects

A

Abdominal pain, headaches

Arthralgia, parasthesia

Confusion, gynaecomastia

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8
Q

H2 antagonists

A

Ranitidine (150mg, 300mg) Cimetidine (200mg, 400mg, 800mg) Famotidine (20mg, 40mg)
Nizatidine (150mg, 300mg)

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9
Q

H2 antagonist dosage forms

A

Tablets
Capsules
Effeverscent tablets
Oral liquids
Injections

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10
Q

H2 antagonist interactions

A

Cimetidine increases blood concentration of erythromycin

Famotidine & Ranitidine reduce plasma concentration of atazanavir

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11
Q

H2 antagonist side effects

A

Diarrhoea, dizziness

Erythema multiform

Hepatitis, confusion

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12
Q

Chelates and complexes

A

Sucralfate (1000mg)
Tripotassium dicitratobismuthate (120mg)

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13
Q

Prostaglandin analogue

A

Misoprostol (200mcg)

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14
Q

Pro-kinetic drugs

A

Domperidone
Metoclopramide

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MP322 (22 decks)

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