Geriatric Flashcards
1
Q
Three acetylcholinesterase inhibitors used in mild to moderate Alzheimer’s
A
donepezil
galantamine
rivastigmine
2
Q
MOA of memantine
A
NMDA receptor antagonist
3
Q
NICE recommend memantine for:
A
- moderate AD but cannot take AChE inhibitors
- add-on to AChE inhibitors in patients with moderate or severe AD
- monotherapy in severe AD
4
Q
MMSE score - mild impairment
A
20 - 24
5
Q
MMSE score - moderate impairment
A
13 - 20
6
Q
MMSE score - severe impairement
A
<12
7
Q
Lewy Body dementia, core clinical features
A
fluctuating cognition
visual hallucinations
parkinsonism
8
Q
Pharmacological management of Lewy Body dementia
A
AChE inhibitors or memantine
