Biosynthesis Of Fatty Acids

Question 1

Synthesis of fatty acids takes place in ?

Answer 1

Cytosol

Question 2

Degradation of fatty acids takes place in ?

Answer 2

Mitochondria

Question 3

What organ does synthesis of fatty acids occur ?

Answer 3

Liver

Question 4

Transporter which takes acetyl co A into the cell comes in form of ?

Answer 4

Citrate

Question 5

IUPAC name for palmitic acid is ?

Answer 5

Hexadecanoic acid (it is the end product)

Question 6

What enzymes are needed for synthesis of higher fatty acid ?

Answer 6

Elongases and desaturases

*propanol is used instead of acetyl coA

Question 7

What converts hexadecanoic acid to unsaturated fatty acid ?

Answer 7

Desaturases (does so by incorporating a double bond)

Question 8

What is a futile cycle ?

Answer 8

Cycle that has no overall effect other than to dissipitate energy in form of heat

Question 9

What is the regulatory step in fatty acid synthesis and what catalyses it?

Answer 9

Formation of MALONYL CO A

catalysed by ACETYL COA CARBOXYLASE
(requires Biotin as a coenzyme)
(Has an alosteric site)

Question 10

What is the ultimate product of fatty acid synthesis ?

Answer 10

Acetyl Co A

Question 11

Ultimate product of fatty acid degradation ?

Answer 11

Palmitoyl co A

Question 12

______ is an allosteric activator of the enzyme Acetyl co A carboxylase

Answer 12

Citrate

Question 13

Fatty acid biosynthesis is also called ?

Answer 13

De novo or Leynen’s spiral

Question 14

NADPH required for biosynthesis is gotten from _______ or ________ and requires ___ moles of NAPH

Answer 14

• pentose phosphate pathway
• malic enzyme
• 14

Question 15

Enzymes involved in ketogenesis

Answer 15

1. HMG CO A LYASE
2. HMG CO A SYNTHASE
3. THIOLASE
4. B-hydroxy butyrate dehydrogenase

Question 16

What does HMG CO A stand for ?

Answer 16

Beta-hydrox-B-methyl glutaryl Co A

Question 17

Routine test for ketone bodies is ?

Answer 17

Rothera’s test