Nomenclature And Apolipoproteins

Question 1

What is a lipoprotein?

Answer 1

Biochemical assembly of protein and lipids

Question 2

Lipoprotein has a hydrophobic core made up primarily of ___ and ____

Answer 2

Cholesterol ester and triacylglycerol

Question 3

Hydrophobic core is surrounded by a hydrophilic membrane consisting of ____, ___ and ___

Answer 3

Phospholipids, cholesterol and apolipoproteins

Question 4

What are apolipoproteins ?

Answer 4

Protein component of plasma lipoprotein

Question 5

Chylomicrons contain Apo __, __, __, __, __ and __

Answer 5

Apo B-48, A-1, A-11, A-V1, A-V, C-11 and C-111

Question 6

Where are Chylomicrons made?

Answer 6

The intestine

Question 7

___ is removed from Chylomicrons to form Chylomicrons remnants?

Answer 7

Triacylglycerol

Question 8

VLDL is produced by the ?

Answer 8

Liver

Question 9

VLDL contains Apo ?

Answer 9

B-100, C-1, C-11, C-111 and Apo -E

Question 10

__ is the core structural protein of VLDL

Answer 10

Apo B-100

Question 11

The size of VLDL depends on the amount of ___ while the size of Chylomicrons depends on the amount of. ___

Answer 11

Triacylglycerol, fat

Question 12

IDL Is formed from the removal of Triacylglycerol by ___ and ___ tissue

Answer 12

Muscle and adipose

Question 13

IDL contains Apo __ and ___

Answer 13

B-100 and Apo -E

Question 14

Chylomicrons remnant and VLDL remnants (IDL) are pro-arthenogenic. True or false ?

Answer 14

True

Question 15

Predominant apolipoprotein of LDL is ?

Answer 15

Apo B-100

Question 16

What is the importance of HDL ?

Answer 16

It plays a role in the reverse transport of cholesterol from peripheral tissues to the liver

• it is anti- Arthenogenic

Question 17

HDL contains Apo ___________

Answer 17

A-1, A-11, C-1, C-11, C-111, A-1V

Question 18

__ is the core protein of HDL

Answer 18

Apo A-1

Question 19

All apolipoprotein A subclasses are synthesized where? Except ___ which is synthesized where ?

Answer 19

The liver

• Apo A-1V synthesized In the small intestine

Question 20

______ enzyme converts cholesterol to cholesterol ester and it is activated by ?

Answer 20

• lesithine cholesterol Acyl transferase
  activated by Apo A-1

Question 21

Apo B-48 is synthesized where ?

Answer 21

Small intestine ( it is exclusively found in the Chylomicrons)

Question 22

___ is the longest known protein to humans?

Answer 22

Apo B-100

Question 23

___ apolipoprotein activates lipoprotein lipase

Answer 23

Apo c-11

*apo c-111 inhibits it