ACE- ARBS

Question 1

Types ACE
uses:
contradiction:
SE
Need to monitor renal function with on ACE or ARB
Can you prescribe this to a pregnant pt?

Answer 1

Types:
Ramipril (Altace)
Lisinopril (Zestril, Prinivil)
Benazepril (Lotensin)

Captopril (Capoten) - causes agranulocytosis, neutropenia, a nd rare leukopenia, monitor CBC

Enalapril (Vasotec)
Fosinopril (Monopril)
Perindopril (Aceon)
Quinapril (Accupril)
Trandolapril (Mavik)

Zestoretic- lisinopril and HCTZ
Vaseretic- enalapril and hctz
Capozide- captopril and HCTZ
Lotrel- benazepril and amlodipine

uses: HTN, DM, CKD, post-MI (increase survival- helps prevent remodeling of the ventricles), and HF/ left ventricle HF (improves EF) * 1st line therapy

Cardiac and renal protection.
contri: in preg (can damage baby ren agio system and lead to death, angioedema, renal stenosis, K above 5.5, do not use in ESCKD GFR below 60.

(blocks Angio I–>angio II)

SE: AKI, angioedema (years later) , hypoten

If the kidney function decreases from 30 % or more from the baseline. (End stage renal) may need to stop the medication.

never prescribe to pregnant women

Question 2

ARB

Types

Answer 2

Losartan (Cozaar)
Irbesartan (Avapro)
Valsartan (Diovan)
Candesartan (Atacand)
Telmisartan (Micardis)
Olmesartan (Benicar)
Eprosartan (Teveten)

combination:
Losartan and HTCS ( Hyzaar)
Valsartan and HTCZ (Diovan HCT)
Valsartan and amlodipine (Exforge)

Question 3

SE

Answer 3

dry cough- first (weeks-months show up)
b/c bradykinins and kallikrein system involved in inflammation process
1) stop and switch to ARB

Question 4

what if a patient has microalbumin in the urine if HTN? which med do you prescribe?

Answer 4

ACE and ARB kidney protection especially in DM