amlodipine

Question 1

what class of drug is this

Answer 1

dihydropyridine class, calcium channel blocker.
antihypertensive

Question 2

MOA

Answer 2

selective for peripheral vasculature.
block L-type calcium channel blockers on smooth muscle cells of arterial blood vessels and cardiac myocytes.
less contraction- less chronotropy and inotropy
lowers TPR
maBP- CO X TPR

Question 3

Common indications?

Answer 3

Especially given to patients with hypertension and low renin. ARBs and ACEi would have no effect on the already low renin in RAAS

Question 4

Drug- drug interactions?

Answer 4

Amlodipine and statin.
this increases the effect of statin by a lot more

Question 5

Adverse drug reactions?

Answer 5

Ankle swelling-
flushing-
headaches- a lot more vasodilation