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Anatomy > Mammalian part 3 > Flashcards

Mammalian part 3 Flashcards

1
Q

Endocytic pathway

A

Everything that comes the cell in

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2
Q

Secretory pathway

A

Everything that the cell excretes

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3
Q

Retrieval pathway

A

Shipping things inside the cell

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4
Q

Endocytosis

A

‘Eating’ the cargo, different forms because of different sizes of the cargo

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5
Q

Phagocytosis

A

Endocytosis of a large solid particle

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6
Q

Pinocytosis

A

Endocytosis of extracellular fluid

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7
Q

Receptor-mediated endocytosis

A

Endocytosis with a coated vesicle

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8
Q

Phosphoinositide

A

Marks vesicle so it knows where to go

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9
Q

SNAREs

A

On recieving membrane to fuse vesicle with membrane

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10
Q

Tethering complex

A

Pulls vesicle closer to membrane so SNAREs can fuse it

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11
Q

NSF complex

A

Untangles SNAREs after vesicle is fused with the membrane

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12
Q

Clathrin coat

A

Responsible for all the vesicles formation traveling inside the cell except ER to Golgi

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13
Q

COP1

A

Coat for vesicle traveling Golgi –> ER

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14
Q

COP2

A

Coat for vesicle traveling ER –> Golgi

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15
Q

N-Glycosylation

A

Posttranslational processing of protein in Golgi, ER–>Golgi

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16
Q

O-glycosylation

A

In Golgi, sugar by sugar, negative charge

17
Q

Proteolic cleavage

A

Post translational processing of golgi in protein

18
Q

Lysosome

A

‘garbage bag’ of the cell

19
Q

Autophagy

A

Recycling of cytoplasm and organelles by lysosomes

20
Q

Mannose 6 phosphate

A

Triggers endosomal targeting and constitutive exocytosis, lysosomal enzymes

21
Q

RAB cascade

A

Early endosome –> lysosome

22
Q

PAMP

A

pathogen molecule (bacteria, virus) that activate PRRs

23
Q

DAMP

A

Host cell molecule that activates PRR

24
Q

PRR

A

Patern recognition center

25
Q

Cytokine

A

Effector molecule that signales, activates sensors (pro or anti inflammantory)

26
Q

Complement system

A

Small molecules produced by liver that recognize infection

27
Q

Phagocytes

A

Seek and destroy pathogens, macrophages, dendtrites and neutrophilic

28
Q

NK cells

A

Kill when abscence of MHC-1, virus infected cells or tumor cells

29
Q

MHC-1

A

Present on cytolytic T-cells, present the antigen

30
Q

MHC-2

A

Present on helper T-cell, present the antigen

31
Q

Effector CD8+ cytolytic T-cell

A

Kills cell that present antigen on MHC-1 (mostly virusus and cancercells)

32
Q

Helper CD4+ T-cells

A

Activates B-Cells

33
Q

Repertoire scanning

A

Manu sequential interactions with different T-cells to find cognate T-cells

Anatomy (10 decks)

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