NSAIDs Flashcards
1
Q
What class of drugs is Celecoxib?
A
NSAIDs
2
Q
What are the common indications of Celecoxib?
A
To reduce swelling and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis
3
Q
What is the mechanism of action of Celecoxib?
A
Selective COX-2 inhibitor. The intention of COX-2 inhibitors was to avoid inhibition of homeostatic actions mediated by COX-1.
4
Q
What are the adverse effects of Celecoxib?
A
Increase risk of MI (Decrease in PGI2 in coronary vasculature)
5
Q
What are the drug-drug interactions of Celecoxib?
A
GI: Aspirin and glucocorticoid steroids and anticoagulants (PPIs should be considered)
Renal: ACEi, ARBs and diuretics
6
Q
How do you remember Celecoxib?
A
