Oogenesis

Question 1

Folliculogenesis

Answer 1

Formation and development of ovarian follicles = endocrine structures that participate in coordination of reproductive cycles and support development of oocyte

Question 2

Oogenesis

Answer 2

Process of differentiation and release of a mature oocyte for fertilization

Question 3

Mitotic Phase

Answer 3

PGCs colonize bipotential gonads - gonads differentiate into ovaries and PCGs differentiate into ooginia

Question 4

Meiotic Phase

Answer 4

Characterized by onset of meiosis and formation of primary oocytes

Question 5

Formation of Primordial follicles

Answer 5

1st layer of granulosa cells creates new biochemical environment within follicle which stimulates differentiation of oogonium

Question 6

Primary Oocytes

Answer 6

Enter meiosis 1 which is then arrested at prophase 1 (diplotene stage)

Question 7

Formation of Germinal Vesicle

Answer 7

Envelope surrounding large oocyte nucleus with arrested, dense DNA

Question 8

Cytoplasmic Development

Answer 8

Characterized by substantial growth of cytoplasm and formation of specialized cellular structures

-activation of primordial follicles

Question 9

Formation of Zona Pellucida

Answer 9

Synthes by oocyte, protects and covers ZP - important for fertilization

Question 10

Formation of Gap Junctions

Answer 10

Cytoplasmic projections from granulosa cells cross ZP, critical for communication btwn granulosa and oocyte, granulosa cells take on many responsibilities for oocyte growth