passmed Flashcards

1
Q

what medical condition can give a falsely low HbA1c

A

sickle cell anaemia

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2
Q

what medical condition can give a falsely high HbA1c

A

splenectomy

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3
Q

Howell-Jolly bodies and siderocytes

A

hyposplenism

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4
Q

treatment after having a venous thromboembolism

A

Venous thromoboembolism - length of warfarin treatment
-provoked (e.g. recent surgery): 3 months
-unprovoked: 6 months

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5
Q

antibiotic of choice for neutropenic sepsis

A

Piperacillin with tazobactam (Tazocin)

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6
Q

isolated thrombocytopenia (low platelets)

A

immune thrombocytopenic prupura

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7
Q

management of von willebrand

A

tranexamic acid for mild bleeding
desmopressin (DDAVP): raises levels of vWF by inducing release of vWF from Weibel-Palade bodies in endothelial cells
factor VIII concentrate

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8
Q

mechanism of action of rivaroxaban

A

direct factor Xa inhibitor

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9
Q

rate of transfusion of RBCs for a non-urgent scenario

A

over 2 hours

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10
Q

raised HbA2?

A

beta thalassaemia trait

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11
Q

Deranged coagulation in sepsis

A

DIC

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12
Q

which blood product has the highest risk of bacterial contamination

A

platelets

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13
Q

antibiotic of choice for neutropenic sepsis

A

Piperacillin with tazobactam (Tazocin)

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14
Q

cause of sudden fall in Hb in someone with sickle cell

A

aplastic crisis

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15
Q

what causes aplastic crisis

A

infection with parovirus

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16
Q

should you give someone with TTP platelets

A

no
-will cause increased risk of death

17
Q

how do you reverse the effects of warfarin

A

vitamin k
-warfarin is a vit k antagonist

18
Q

heinz bodies

A

G6PD