DRUGS Flashcards
what type of drug is aspirin
anti-platelet
mechanism of action of aspirin
inhibits cyclo-oxygenase
when should you stop aspirin before an elective opertation
7 days prior
how do you reverse effects of aspirin in serious bleeding
platelet transfusion
what type of drug is clopidogrel
anti-platelet
mechanism of action of clopidogrel
ADP receptor antagonists
when should you stop clopidogrel before operations
7 days
mechanism of action of dipyridamole
Phosphodiesterase inhibitor - increases production of cAMP which inhibits platelet aggregation
what type of drug is heparin
anti-coagulant
how quickly is the effect of heparin
immediately
how do you monitor unfractioned heparin
APTT
how do you reverse heparin in severe bleeding
protamine sulphate
mechanism of action of warfarin
inhibit vitamin K
-factors II, VII, IX and X require vitamin K
how do you monitor warfarin
INR
warfarin reversal
-omit warfarin dose
-administer oral vit K (works in 6 hours)
-administer clotting faactors
-clinical and laboratory assessment of response
