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Flashcards in 13 Deck (45):
1

Leukemia associated with HTLV1

T cell leukemia

2

Leukemia associated with EBV

Burkitt lymphoma (and some hodgkin lymphoma)

3

Leukemia associated with KSHV/HHV8

Kaposi sarcoma, b cell lymphoma (presents with pleural effusion)

4

PIGA

paroxysmal nocturnal hemoglobinuria

5

BRAF

hairy cell leukemia (BIG spleen)

6

c-myc

burkitt lymphoma

7

hodgkin subtype that is EBV- CD15- and CD30-

lymphocyte dominant

8

popcorn cells

lymphocyte dominant hodgkin

9

prognosis for kid diagnosed with BALL

good- t12:21
bad- t9:22

10

blood finding of kid with BALL

pancytopenia

11

mutation in TALL

NOTCH1

12

this cancer is CD+ for 5, 19, 20, 23 and often asymptomatic

CLL / SLL

13

smudge cells

CLL

14

what can undergo richter transformation to become DLBCL

CLL or follicular lymphoma

15

BCL6, myc, bcl2, cd 19, cd 20, EBV+

DLBCL

16

this entity presents as a rapidly growing mass in LN or spleen (can be at waldeyer ring)

DLBCL

17

bcl2+ t14:18 indolent but incurable cancer

follicular lymphoma (general LAD)

18

markers for burkitt

EBV, myc, cd 10 19 20

19

starry sky appearance

burkitt

20

prognostic indicator for multiple myeloma

IL6 (poor) , cyclin d1 (good)

21

cd markers 138 and 56 indicate

multiple myeloma

22

myd88, cd20, igM positive cells

lymphoplasmacytic lymphoma

23

whats waldenstrom macroglobulinemia

igM overload causes hyper viscosity of blood

24

basophilia

cml

25

normal amount but large size platelets that have glycoprotein deficiency so vWF cannot do its job

bernard soulier

26

low platelet count in young female <40 yo with petichea and normal PT and PTT

ITP

27

Tx for ITP

splenectomy

28

Ab's are what subtype for warm agglutination

IgG

29

Ab's are what subtype for cold agglutination

IgM

30

Ab's are what subtype for ITP

IgG

31

inheritance for vWF disease

auto dom

32

tx for vWF disease

desmopressin or new plasma

33

translocation associated with follicular lymphoma

14 18 (bcl2)

34

translocation associated with burkitt lymphoma

8 14 (myc)

35

translocation associated with mantle cell lymphoma

11 14 (cyclin d1)

36

cerebriform nuclei

cd 4 cells in mycosis fungiodes

37

sezary syndrome

mycosis fungiodes: cerebriform nuclei cd4 cells have entered the blood

38

bierbeck granules

tennis rackets - langerhans cell histiocytosis

39

folate is absorbed in the

jejunum

40

B12 is absorbed in the

ileum

41

whats pernicious anemia

parietal cell destruction (no IF making means no B12 absorbed)

42

paroxysmal nocturnal dyspnea is detected using what cell marker

cd55

43

heinz body

G6pd def

44

bite cells

g6pd def

45

inheritance for g6pd def

x linked recessive