13

Question 1

Leukemia associated with HTLV1

Answer 1

T cell leukemia

Question 2

Leukemia associated with EBV

Answer 2

Burkitt lymphoma (and some hodgkin lymphoma)

Question 3

Leukemia associated with KSHV/HHV8

Answer 3

Kaposi sarcoma, b cell lymphoma (presents with pleural effusion)

Question 4

PIGA

Answer 4

paroxysmal nocturnal hemoglobinuria

Question 5

BRAF

Answer 5

hairy cell leukemia (BIG spleen)

Question 6

c-myc

Answer 6

burkitt lymphoma

Question 7

hodgkin subtype that is EBV- CD15- and CD30-

Answer 7

lymphocyte dominant

Question 8

popcorn cells

Answer 8

lymphocyte dominant hodgkin

Question 9

prognosis for kid diagnosed with BALL

Answer 9

good- t12:21

bad- t9:22

Question 10

blood finding of kid with BALL

Answer 10

pancytopenia

Question 11

mutation in TALL

Answer 11

NOTCH1

Question 12

this cancer is CD+ for 5, 19, 20, 23 and often asymptomatic

Answer 12

CLL / SLL

Question 13

smudge cells

Answer 13

CLL

Question 14

what can undergo richter transformation to become DLBCL

Answer 14

CLL or follicular lymphoma

Question 15

BCL6, myc, bcl2, cd 19, cd 20, EBV+

Answer 15

DLBCL

Question 16

this entity presents as a rapidly growing mass in LN or spleen (can be at waldeyer ring)

Answer 16

DLBCL

Question 17

bcl2+ t14:18 indolent but incurable cancer

Answer 17

follicular lymphoma (general LAD)

Question 18

markers for burkitt

Answer 18

EBV, myc, cd 10 19 20

Question 19

starry sky appearance

Answer 19

burkitt

Question 20

prognostic indicator for multiple myeloma

Answer 20

IL6 (poor) , cyclin d1 (good)

Question 21

cd markers 138 and 56 indicate

Answer 21

multiple myeloma

Question 22

myd88, cd20, igM positive cells

Answer 22

lymphoplasmacytic lymphoma

Question 23

whats waldenstrom macroglobulinemia

Answer 23

igM overload causes hyper viscosity of blood

Question 24

basophilia

Answer 24

cml

Question 25

normal amount but large size platelets that have glycoprotein deficiency so vWF cannot do its job

Answer 25

bernard soulier

Question 26

low platelet count in young female <40 yo with petichea and normal PT and PTT

Answer 26

ITP

Question 27

Tx for ITP

Answer 27

splenectomy

Question 28

Ab’s are what subtype for warm agglutination

Answer 28

IgG

Question 29

Ab’s are what subtype for cold agglutination

Answer 29

IgM

Question 30

Ab’s are what subtype for ITP

Answer 30

IgG

Question 31

inheritance for vWF disease

Answer 31

auto dom

Question 32

tx for vWF disease

Answer 32

desmopressin or new plasma

Question 33

translocation associated with follicular lymphoma

Answer 33

14 18 (bcl2)

Question 34

translocation associated with burkitt lymphoma

Answer 34

8 14 (myc)

Question 35

translocation associated with mantle cell lymphoma

Answer 35

11 14 (cyclin d1)

Question 36

cerebriform nuclei

Answer 36

cd 4 cells in mycosis fungiodes

Question 37

sezary syndrome

Answer 37

mycosis fungiodes: cerebriform nuclei cd4 cells have entered the blood

Question 38

bierbeck granules

Answer 38

tennis rackets - langerhans cell histiocytosis

Question 39

folate is absorbed in the

Answer 39

jejunum

Question 40

B12 is absorbed in the

Answer 40

ileum

Question 41

whats pernicious anemia

Answer 41

parietal cell destruction (no IF making means no B12 absorbed)

Question 42

paroxysmal nocturnal dyspnea is detected using what cell marker

Answer 42

cd55

Question 43

heinz body

Answer 43

G6pd def

Question 44

bite cells

Answer 44

g6pd def

Question 45

inheritance for g6pd def

Answer 45

x linked recessive