Leukaemia Flashcards

1
Q

What is the first line management of chronic myeloid leukaemia?

A

Tyrosine kinase inhibitor (imatinib)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the genetic defect in 95% of CML?

A

Philadelphia chromosome
Translocation leads to permanent activation of BCR gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly