INBDE - DIABETE

Question 1

Glipizide, glyburide, glimepiride (Sulfonylureas)

Answer 1

MOA:
* Increase insulin secretion by β cells

CHARACTERISTICS:
* Sulfonylurea + Ibuorofen = Hypoglycemia

https://www.medicalnewstoday.com/articles/drugs-glipizide-oral-tablets

Question 2

Metformin

Answer 2

MOA:
* Decrease hepatic glucose production (or decrease glucagonproduction)
* Decrease intestinal absorption of glucose
* Decrease gluconeogenesis
* Increase peripheral glucose uptake
* Inhibits glucagon
* Improves insulin sensitivity of tissue

https://www.medicalnewstoday.com/articles/metformin-oral-tablet

Question 3

Januvia (Sitagliptin, linagliptin, saxagliptin)

Answer 3

MOA:
* Dipeptidyl Peptidase-4 Inhibitor

https://www.medicalnewstoday.com/articles/325698

Question 4

Proglitazone, Avandia (rosiglitazone)

Answer 4

MOA:
* Thiazolidinedione

https://www.medicalnewstoday.com/articles/avandia

Question 5

Arcabose, miglitol

Answer 5

MOA:
* Α-glucosidase Inhibitor

https://www.medicalnewstoday.com/articles/311300#medications-for-type-2-diabetes

Question 6

Canagliflozin, dapagliflozin, empagliflozin

Answer 6

MOA:
* SGLT2 Inhibitor