INBDE - ANTICOAGULANTS Flashcards
1
Q
Warfarin
A
MOA:
* Blocks reduction recycling of vitamin K (blocking factors ll, Vll, lX and X)
* Interfere in factors II, VII, IX, X.
CHARACTERISTICS:
* Inhibits vitamin K
* Vegan diet increase INR
* Acetaminophen, garlic, ginger – increase INR
2
Q
Heparin
A
MOA:
* Pulls thrombin and anti-thrombin together (blocking factor ll)
CHARACTERISTICS:
* Given to prevent clot formation in cases of
dialysis. The risk of bleeding will have
decreased by 24h following dialysis. (Dialysis:
cirurgia menor 1 dia/cirurgia maior entre as
sessões//Heparin leva 24h para sair do corpo)
https://www.medicalnewstoday.com/articles/heparin-injectable-solution
3
Q
Apixaban (Eliquis), rivaroxaban
A
MOA:
* Selective inhibits factor Xa
4
Q
Dabigatran (Pradaxa)
A
MOA:
* Directly binds to thrombin (factor lla)
