Gram negative bacilli (non-enterics) Flashcards

1
Q

Haemophilus influenza Morphology/Structure

A

Gram negative
coccobacillus, facultative
anaerobe

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2
Q

Haemophilus influenza Virulence Factors

A

b polysaccharide
capsule, adhesion
proteins

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3
Q

Haemophilus influenza Diseases/Symptoms

A

Acute bacterial meningitis,
Symptoms include: fever,
stiff neck, vomiting,
neurological impairment

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4
Q

Haemophilus influenza Diagnostics

A

H. influenzae
cultured from
usually sterile
sites (e.g.,
cerebrospinal
fluid)

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5
Q

Haemophilus influenza Prevention/Treatment

A

Vaccine (Hib)
vaccine is against
b polysaccharide
capsule.
Amoxicillin and
cephalosporin.

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6
Q

Haemophilus influenza Immune Response

A

Can be part of
normal flora that
crosses bloodbrain barrier

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7
Q

Haemophilus influenza Modes of Transmission

A

Upper respiratory
tract of humans
form that has
capsule is
pathogenic

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8
Q

Pseudomonas
aeruginosa Morphology/structure

A

Gram negative rod, flagella,
aerobic

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9
Q

Pseudomonas
aeruginosa Modes of Transmission

A

Many people can
be asymptomatic
carrier, People in
hospitals,
swimming pools,
moist environments

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10
Q

Pseudomonas
aeruginosa Virulence Factors

A

Exotoxins, biofilms,
pyocyanin kills nasal
cilia, pyoverdin steals
host iron

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11
Q

Pseudomonas
aeruginosa Diseases/symptoms

A

UTI, bed sores,
Opportunistic and
nosocomial of
immunocompromised.
Can also lead to jacuzzi
rash (usually self limiting)

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12
Q

Pseudomonas
aeruginosa Diagnostics

A

Mac Conkey
agar - nonlactose
fermentor.
Oxidase positive,
rotting fruit odor

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13
Q

Pseudomonas
aeruginosa Prevention/Treatment

A

Multi drug
resistant.
Aminoglycosides
and
cephalosporins
have been known
to be effective,
some strains need
to use Imipenem

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14
Q

Pseudomonas
aeruginosa Immune Response

A

Opportunistic,
nosocomial
pathogen of
immunocompromi
sed. Also, people
with cystic
fibrosis can live in
excess mucus
and cause death.

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15
Q

Bordetella pertussis Morphology/structure

A

Gram negative, Coccobacillus, aerobic

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16
Q

Bordetella pertussis Modes of Transmission

A

Not normal flora of
human respiratory
tract, true
pathogen

17
Q

Bordetella pertussis Virulence Factors

A

Capsule, Pertussis
toxin

18
Q

Bordetella pertussis Diseases/Symptoms

A

Whooping Cough; mostly in
children, symptoms inc
lude: runny nose,
sneezing, fever, dry cough
makes whooping sound

19
Q

Bordetella pertussis Diagnostics

A

Gram negative,
cocobacili,
diplococci
arrangement on
gram stain.
Cephalosporin
sensitive

20
Q

Bordetella pertussis Prevention/Treatment

A

Cephalosporin,
Azithromycin,
Vaccine DTP or
DTPH

21
Q

Bordetella pertussis Immune Response

A

Infants younger
than 12 months
have highest risk
for severe or life
threatening
conditions