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dermato > toxidermie > Flashcards

toxidermie Flashcards

1
Q

toxidermie def :

A

effets cutanée secondaire à la prise de médoc = immuno ou non immuno

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2
Q

urticaire : lésions

A

érythème fugace, mobile

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3
Q

exanthème maculo-papuleux = temporalité

A

4-14j

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4
Q

exanthème pigmenté fixe = etiologie + temporalité

A

AINS + paracétamol
<48h

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5
Q

PEAG : temporalité

A

1-11j

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6
Q

Lyell + stenvens jonhons temporalité

A

4-28j

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7
Q

DRESS sd : temporalité

A

2-6 sem

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8
Q

quelle lésions est pathognomonique de la toxidermie

A

exanthème pigmenté fixe

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9
Q

% DECOLLEMENT CUTANE si Johnson ou si lyell

A

Johnson : <10%
Lyell >30%

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10
Q

formes de toxidermies=

A

urticaire
photo-sensibilité (tox + allergie)
choc anaphylactique
exanthème pigmenté fixe
exanthème maculo-papuleux
PEAG
sd stevens johnson
sd Lyell
DRESS sd
reaction cut sous TNF a
lupus induit

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11
Q

photo-allergie temporalité

A

7-21j

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12
Q

photo-toxicité : temporalité

A

qqlm h

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13
Q

différence biologique entre exanthème maculo-papuleux + PEAG + DRESS sd

A

exanthème maculo-papuleux : hypereosinophilie modéré <1000/mm3
PEAG = pnn+++
DRESS sd : hypereosino >1500/mm3

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14
Q

PEAG : médoc incriminé

A

ATB

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15
Q

exanthème pigmenté fixe médoc incriminé

A

AINS + paracétamol

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16
Q

exanthème maculo-papuleux :

A

peni A, B lact, antiBK, anti Kc

17
Q

sd johnson / Lyell =

A

sulfamide, allopurinol, anti-comitiaux, AINS, nevirapide

18
Q

dress sd

A

anti comitiaux, IPP, produit contraste, sulfamide

19
Q

en cas de DRESS sd : bilan

A

NFS(pnn), bilan R bilan H

20
Q

% hospitalisation du a la iatrogénie

A

10 %

21
Q

forme les plus fréquente de toxidermie =

A

érythème maculeux-papuluex
urticaire

22
Q

localisation préférentielle de erythme pigmenté fixe =

A

OGE
levre

23
Q

DD de la PEAG =

A

psoriasis pustuleux généralisés

24
Q

type d’exanthème dans la PEAG =

A

érythème scarlatiforme en nappe dans les grands plis avec pustules amicrobienne superficielle

25
Q

bio du DRESS sd

A

hypereosinophilie >1500/mm3
lymphocytose

26
Q

bio PEAG =

A

PNN

27
Q

quelle sont les formes les plus grave toxidermies ?

A

Lyell + stevens johson

28
Q

DD du sd stevens jonhobs =

A

érythème polymorphe majeur

29
Q

DD Lyell :

A

epidermolyse staph
DBAI
brulure

30
Q

lésons évocateurs DRESS sd =

A

lésions ++ étendu, oèdeme visage, lésions infiltré

31
Q

lésions évocateurs NET (Lyell, SJ)

A

érosions muqueuse, lésions vésiculeuse, bulleuse,

32
Q

FDR toxidermie :

A

VIH
Immunosuppression
MNI en cours
PAS ATOPIE

dermato (13 decks)

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