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CPT Drugs > Opioids > Flashcards

Opioids Flashcards

1
Q

Weak Mu receptor agonists

A

Tramadol

Codeine:
prodrug that is converted to morphine by CYP2D6
Fluoxetine (SSRIs) - CYP2D6 inhibitors so need ^dose

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2
Q

Strong Mu receptor agonists

A

Morphine
Fentanyl
Diamorphine

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3
Q

Mixed Mu receptor partial agonist

A

Buprenorphine

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4
Q

Opioid indications

A

Analgesia
Antitussive (cough suppression)
Palliation
Anti-diarroheal

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5
Q

Opioid ADRs

A

Constipation
Drowsiness
Dysphoria (euphoria initially)
Miosis
Respiratory distress

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6
Q

Opioid DDIs

A

CNS depressants
Reduced gut motility drugs

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7
Q

Contraindications

A

Comatose patients
^ICP
Constipation
Manual labour/drivers

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8
Q

Opioid OD treatment?

A

Naloxone

Competitive opioid receptor antagonist

(signs of OD - slow breathing, slow HR)

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9
Q

Opioid addiction treatment?

A

Buprenorphine (partial agonist/antagonist)

Methadone (higher affinity to receptors than others)

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CPT Drugs (19 decks)

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